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European multi-cent...
European multi-centre study on coeliac disease and non-Hodgkin lymphoma.
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- Luisa Mearin, M (author)
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- Catassi, Carlo (author)
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- Brousse, Nicole (author)
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- Brand, Ronald (author)
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- Collin, Pekka (author)
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- Fabiani, Elisabetta (author)
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- Schweizer, Joachim J. (author)
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- Abuzakouk, Mohamed (author)
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- Szajewska, Hania (author)
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- Hallert, Claes, 1945- (author)
- Linköpings universitet,Östergötlands Läns Landsting,Närsjukvården i östra Östergötland,Hälsa, Aktivitet, Vård (HAV),Hälsouniversitetet
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- Farré Masip, Carme (author)
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Holmes, Geoffrey K.T. (author)
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(creator_code:org_t)
- 2006
- 2006
- English.
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In: European Journal of Gastroenterology and Hepathology. - 0954-691X .- 1473-5687. ; 18:2, s. 187-194
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http://journals.lww....
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https://urn.kb.se/re...
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Abstract
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- Introduction: Coeliac disease (CD) is associated with an increased risk of non-Hodgkin lymphoma (NHL), but there is little information about whether this is true for clinically silent CD. Objective: To investigate the frequency of CD in two European populations; one with NHL and another derived from the general population. Methods: A prospective, multi-centre, case-control study in 10 European countries was conducted between May 1998 and April 2001. A total of 1446 consecutive patients with newly diagnosed NHLaged over 18 years was collected. The control group consisted of a population of 9676 individuals who were screened for CD. The number of patients with a previous diagnosis of CD and those with silent CD detected by screening were determined in the two groups. Results: The patients with CD had a significantly increased risk of developing NHL [odds ratio (OR) 2.6, 95% confidence interval (CI) 1.4-4.9]. This risk was only present in patients with CD diagnosed clinically before the study (OR 3.3, 95% CI 1.4-7.9), but not in those with silent CD detected by screening (OR 1.3, 95% CI 0.6-2.7). Conclusion: Patients with CD have an increased risk of developing NHL, although this is lower than previously thought. Clinically silent CD is rare in patients with NHL.
Keyword
- Coeliac disease
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Luisa Mearin, M
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Catassi, Carlo
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Brousse, Nicole
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Brand, Ronald
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Collin, Pekka
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Fabiani, Elisabe ...
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show more...
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Schweizer, Joach ...
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Abuzakouk, Moham ...
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Szajewska, Hania
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Hallert, Claes, ...
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Farré Masip, Car ...
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Holmes, Geoffrey ...
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show less...
- Articles in the publication
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European Journal ...
- By the university
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Linköping University