onr:"swepub:oai:DiVA.org:liu-25843"
Search: onr:"swepub:oai:DiVA.org:liu-25843" > Polyunsaturated n-3...
- 1 of 1
- Previous record
- Next record
- To hitlist
- Duchen, Karel,1961-Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Pediatrik,Barn (author)
Polyunsaturated n-3 fatty acids and the development of atopic disease
- Article/chapterEnglish2001
Publisher, publication year, extent ...
- 2001
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:liu-25843
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-25843URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- The relationship between polyunsaturated longchain fatty acids and atopy has been discussed for decades. Higher levels of the essential fatty acids linoleic acid and a-linolenic acid and lower levels of their longer metabolites in plasma phospholipids of atopic as compared to nonatopic individuals have been reported by several, but not all, studies. Largely similar findings have been reported in studies of cell membranes from immunological cells from atopics and nonatopics despite differences in methodology, study groups, and definitions of atopy. An imbalance in the metabolism of the n-6 fatty acids, particularly arachidonic acid and dihomo-?-linolenic acid, leading to an inappropriate synthesis of prostaglandin (PG) E2 and PGE1 was hypothesized early on but has not been corroborated. The fatty acid composition of human milk is dependent on the time of lactation not only during a breast meal but also the time of the day and the period of lactation. This explains the discrepancies in reported findings regarding the relationship between milk fatty acids and atopic disease in the mother. Prospective studies show disturbances in both the n-6 and n-3 fatty acid composition between milk from atopic and nonatopic mothers. Only the composition of long-chain polyunsaturated n-3 fatty acids was related to atopic development in the children, however. A relationship between lower levels of n-3 fatty acids, particularly eicosapentaenoic acid (20:5 n-3), and early development of atopic disease is hypothesized.
Subject headings and genre
- MEDICINE
- MEDICIN
Added entries (persons, corporate bodies, meetings, titles ...)
- Björkstén, BengtÖstergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Pediatrik,Barn (author)
- Linköpings universitetHälsouniversitetet (creator_code:org_t)
Related titles
- In:Lipids36:9, s. 1033-10420024-42011558-9307
Internet link
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Duchen, Karel, 1 ...
- Björkstén, Bengt
- Articles in the publication
- Lipids
- By the university
- Linköping University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
