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Influence of tissue...
Influence of tissue movement on laser Doppler perfusion imaging
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- Karlsson, Daniel M G, 1974- (author)
- Linköpings universitet,Institutionen för medicinsk teknik,Tekniska högskolan,Biomedicinsk instrumentteknik
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- Larsson, Marcus, 1974- (author)
- Linköpings universitet,Institutionen för medicinsk teknik,Tekniska högskolan
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- Strömberg, Tomas, 1966- (author)
- Linköpings universitet,Institutionen för medicinsk teknik,Tekniska högskolan,Biomedicinsk instrumentteknik
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- Wårdell, Karin, 1959- (author)
- Linköpings universitet,Institutionen för medicinsk teknik,Tekniska högskolan,Biomedicinsk instrumentteknik
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(creator_code:org_t)
- SPIE, 2002
- 2002
- English.
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In: <em></em><em>Proc. SPIE</em> 4624, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II, 106 (May 24, 2002), Vol. 4624. - : SPIE. ; , s. 106-114, s. 106-114
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- The microvascular perfusion can be measured using laser Doppler blood flowmetry (LDF), a technique sensitive to the concentration of moving blood cells and their velocity. However, movements of the tissue itself can cause artifacts in the perfusion readings. In a clinical situation, these movement induced artifacts may arise from patient movements or from movements of internal organs e.g. the intestines or the beating heart. Therefore, we have studied how a well-controlled tissue movement affects the LDF signals during different flow conditions and for different surface structures. Tissue perfusion was recorded non-touch in one point using a laser Doppler perfusion imager. During the measurements the object was placed on a shaker that generated the movement (both horizontal and vertical). Measurements were carried out both on DELRIN® (polyacetal plastic) and the fingertip, for a wide range of velocities (0-3 cm/s). The influence of the microvascular perfusion was evaluated by occluding the brachial artery as well as blood emptying the finger and by using a flow model. The LDF signals were correlated to the movement. In vivo measurements showed that velocities above 0.8 cm/s gave a significant contribution to the perfusion signal. Corresponding velocities for the DELRIN® piece were higher (1.4 – 2.6 cm/s), and dependent on the surface structures and reflecting properties. By reducing the amount of specular reflection the movement influence was substantially lowered.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- kon (subject category)
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