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The effect of percu...
The effect of percutaneous dilatation of renal arterial stenosis on captopril renography in hypertension
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Anfelter, P (author)
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- Granerus, Göran, 1939- (author)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Klinisk fysiologi,Fysiologiska kliniken
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- Stenström, Hugo, 1949- (author)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Medicinsk radiologi,Avdelningen för radiologi US
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- Eriksson, Per, 1958- (author)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Reumatologi,Länskliniken för Reumatologi i Östergötland
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- Nyström, Fredrik, 1963- (author)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Internmedicin,Endokrin- och magtarmmedicinska kliniken US
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(creator_code:org_t)
- 2009-07-08
- 2005
- English.
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In: Blood Pressure. - : Informa UK Limited. - 0803-7051 .- 1651-1999. ; 14:6, s. 359-365
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Background. The clinical effects of percutaneous transluminal renal artery angioplasty (PTRA) in patients with renal vascular stenosis and hypertension is controversial. Methods. We consecutively recruited all 23 patients referred for evaluation of renovascular hypertension that eventually underwent unilateral PTRA, to be investigated with captopril MAG3 renography (CR), both before and after the endovascular procedure. Data were evaluated on an intention-to-treat basis. Results. We found that the relative MAG3 clearance of the stenotic kidney increased (from 29.9 ± 14% to 35.1 ± 14%, p=0.01) and that the creatinine levels fell following the intervention (from 110 ± 19 to 99 ± 17 μmol/l, p=0.0003). Blood pressure levels were also lowered (from 173 ± 32/93 ± 17 to 158 ± 31/86 ± 15 mmHg, p<0.006) while the mean number of anti-hypertensive drugs was unchanged following PTRA (2.9 ± 1.4 before and 2.8 ± 1.3 drugs after the intervention, respectively, p-0.6). Conclusion. This prospective trial showed statistically significant improvements of individual kidney function as measured by CR and blood pressure in subjects with suspected renovascular hypertension treated with PTRA. Although the endovascular procedure was found to be safe, the magniture of the absolute improvements was rather modest. © 2005 Taylor & Francis.
Keyword
- Captopril
- hypertension
- outcome
- renal artery stenosis
- renography
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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