Search: onr:"swepub:oai:DiVA.org:liu-32567" >
Red Blood Cell Velo...
Red Blood Cell Velocity and Volumetric Flow Assessment by Enhanced High-Resolution Laser Doppler Imaging in Separate Vessels of the Hamster Cheek Pouch Microcirculation
-
- Golster, Helena (author)
- Linköpings universitet,Anestesiologi med intensivvård,Hand och plastikkirurgi,Hälsouniversitetet
-
- Lindén, Maria, 1965- (author)
- Linköpings universitet,Institutionen för medicinsk teknik,Hälsouniversitetet
-
- Bertuglia, Silvia (author)
- CNR Institute of Clinical Physiology, Pisa, Italy
-
show more...
-
- Calantuoni, Antonio (author)
- CNR Institute of Clinical Physiology, Pisa, Italy
-
- Nilsson, Gert, 1947- (author)
- Linköpings universitet,Institutionen för medicinsk teknik,Hälsouniversitetet
-
- Sjöberg, Folke, 1956- (author)
- Linköpings universitet,Anestesiologi med intensivvård,Hand och plastikkirurgi,Hälsouniversitetet
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 1999
- 1999
- English.
-
In: Microvascular Research. - : Elsevier BV. - 0026-2862 .- 1095-9319. ; 58:1, s. 62-73
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- An enhanced high-resolution laser Doppler imager (EHR-LDI), configured to fit the demands of a measurement area containing separate microvessels, was evaluated for perfusion measurements in hamster cheek pouch preparations during ischemia, reperfusion, and pharmacologically induced vasodilation and vasoconstriction. Measurements in separate microvessels where the laser beam was smaller than the vessel diameter were referred to as red blood cell (RBC) velocity estimates, as previously validated in vitro, whereas a relative flow index, RFI (mean RBC velocity/tissue area), was introduced as a volumetric flow measure. Microvessel diameter and RBC velocity changes during ischemia, reperfusion, as well as during vasoconstriction and vasodilation correlated to the data obtained from the microscope. Correspondingly, during the described provocations anticipated volumetric flow changes were registered as changes in the RFI. When data on intravessel RBC velocity profiles are presented they reflect a parabolic flow profile usually seen in this size microvessel. The EHR-LDI appears a promising tool for investigation of the microvasculature, as it almost simultaneously provides information on relative changes of both in vivo RBC velocity and volumetric flow (RFI), although the latter estimate needs to be further refined.
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database