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Influence of perica...
Influence of pericardial suction blood retransfusion on memory function and release of protein S100B
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- Svenmarker, Staffan (author)
- Umeå universitet,Kirurgi
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- Engström, Karl Gunnar (author)
- Umeå universitet,Kirurgi
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- Karlsson, Thomas, 1953- (author)
- Linköpings universitet,Filosofiska fakulteten,Avdelningen för kognition, utveckling och handikapp, CDD
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Jansson, E. (author)
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Lindholm, R. (author)
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Åberg, T. (author)
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(creator_code:org_t)
- 2016-06-30
- 2004
- English.
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In: Perfusion. - : SAGE Publications. - 0267-6591 .- 1477-111X. ; 19:6, s. 337-343
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https://doi.org/10.1...
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Abstract
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- Background: To study the influence of pericardial suction blood (PSB) on postoperative memory disturbances and release patterns of protein S100B during and after cardiopulmonary bypass (CPB). Methods: Sixty male patients admitted for coronary artery bypass surgery were prospectively randomized to receive PSB either by using conventional cardiotomy suction retransfusion or after cell-saver processing. Results: The concentration of S100B rose during the period of CPB from 0.065 ± 0.004 to 0.24 ± 0.001 μg/L (p <0.001). PSB contained 18.0 ± 1.7 μg/L of S100B. Direct retransfusion from the cardiotomy reservoir made the systemic level increase to 1.42 ± 0.19 μg/L compared to 0.25±0.02 μg/L using a cell-saver. Signs of postoperative memory dysfunction (>1 SD) were discovered in one of three tests, but were unrelated to technique of retransfusion. No associations were found between serum concentrations of S100B and memory function. Conclusion: In this study, retransfusion of PSB during cardiac surgery appeared not to cause memory disturbances. PSB contained high concentrations of protein S100B making its use as a marker of cerebral injury unsuitable. © Arnold 2004.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- SOCIAL SCIENCES
- SAMHÄLLSVETENSKAP
Publication and Content Type
- ref (subject category)
- art (subject category)
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