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Fibrillating areas ...
Fibrillating areas isolated within the left atrium after radiofrequency linear catheter ablation
- Article/chapterEnglish2006
Publisher, publication year, extent ...
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Wiley,2006
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:liu-37267
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-37267URI
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https://doi.org/10.1111/j.1540-8167.2006.00505.xDOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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INTRODUCTION: Nonpulmonary vein sources have been implicated as potential drivers of atrial fibrillation (AF). This observational study describes regions of fibrillating atrial tissue isolated inadvertently from the left atrium (LA) following linear catheter ablation for AF. METHODS AND RESULTS: We report four patients with persistent/permanent AF who underwent pulmonary vein isolation with additional linear lesions and who presented with recurrent AF (mean AF cycle length [AFCL] 175-270 ms). Further catheter ablation resulted in the inadvertent electrical isolation of significant areas of the LA in which AF persisted at the same AFCL as was measured prior to disconnection, despite the restoration of sinus rhythm (SR) in all other left and right atrial areas, strongly suggesting that these islands were driving the remaining atria into fibrillation. The disconnected areas were located in the lateral LA, including the left atrial appendage (LAA) in three patients (limited to the LAA in one) and in the posterior LA in one patient. These isolated fibrillating regions represented 15-24% of the global LA surface, as estimated by electroanatomic mapping. CONCLUSION: Fibrillation can be maintained within electrically isolated regions of the LA following catheter ablation of AF, demonstrating the importance of atrial drivers in the maintenance of AF. Further mapping of these drivers is needed to characterize their mechanism and thereby allow for a more specific ablation strategy.
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Rotter, Martin
(author)
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Sanders, Prashanthan
(author)
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Jais, Pierre
(author)
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Hocini, Mélèze
(author)
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Takahashi, Yoshihide
(author)
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Sacher, Fréderic
(author)
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Jönsson, Anders,1962-Hôpital Cardiologique du Haut-Lévêque
(author)
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ONeill, Mark D
(author)
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Hsu, Li-Fern
(author)
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Clémenty, Jacques
(author)
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Haissaguerre, Michel
(author)
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Hôpital Cardiologique du Haut-Lévêque
(creator_code:org_t)
Related titles
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In:Cardiovascular Electrophysiology: Wiley17, s. 807-8121045-38731540-8167
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Rostock, Thomas
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Rotter, Martin
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Sanders, Prashan ...
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Jais, Pierre
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Hocini, Mélèze
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Takahashi, Yoshi ...
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Sacher, Fréderic
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Jönsson, Anders, ...
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ONeill, Mark D
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Hsu, Li-Fern
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Clémenty, Jacque ...
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Haissaguerre, Mi ...
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Cardiovascular E ...
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Linköping University