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Intracerebral micro...
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Wårdell, KarinLinköpings universitet,Biomedicinsk instrumentteknik,Tekniska högskolan,MINT
(author)
Intracerebral microvascular measurements during deep brain stimulation implantation using laser doppler perfusion monitoring
- Article/chapterEnglish2007
Publisher, publication year, extent ...
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2007-08-17
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S. Karger,2007
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electronicrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-48444
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-48444URI
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https://doi.org/10.1159/000107360DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-25731URI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The aim of the study was to investigate if laser Doppler perfusion monitoring (LDPM) can be used in order to differentiate between gray and white matter and to what extent microvascular perfusion can be recorded in the deep brain structures during stereotactic neurosurgery. An optical probe constructed to fit in the Leksell® Stereotactic System was used for measurements along the trajectory and in the targets (globus pallidus internus, subthalamic nucleus, zona incerta, thalamus) during the implantation of deep brain stimulation leads (n = 22). The total backscattered light intensity (TLI) reflecting the grayness of the tissue, and the microvascular perfusion were captured at 128 sites. Heartbeat-synchronized pulsations were found at all perfusion recordings. In 6 sites the perfusion was more than 6 times higher than the closest neighbor indicating a possible small vessel structure. TLI was significantly higher (p < 0.005) and the perfusion significantly lower (p < 0.005) in positions identified as white matter in the respective MRI batch. The measurements imply that LDPM has the potential to be used as an intracerebral guidance tool.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Blomstedt, PatricUmeå universitet,Neurokirurgi,Department of Neurosurgery, University Hospital, Umeå, Sweden(Swepub:umu)pabl0002
(author)
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Richter, JohanLinköpings universitet,Tekniska högskolan,Biomedicinsk instrumentteknik,MINT(Swepub:liu)johri42
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Antonsson, JohanLinköpings universitet,Tekniska högskolan,Biomedicinsk instrumentteknik(Swepub:liu)johan25
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Eriksson, OlaLinköpings universitet,Tekniska högskolan,Biomedicinsk instrumentteknik(Swepub:liu)olaer67
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Zsigmond, PeterÖstergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Neurokirurgi,Neurokirurgiska kliniken US(Swepub:liu)petzs86
(author)
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Bergenheim, A TommyUmeå universitet,Neurokirurgi,Department of Neurosurgery, University Hospital, Umeå, Sweden(Swepub:umu)tobe0004
(author)
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Hariz, Marwan IUmeå universitet,Neurokirurgi,Department of Neurosurgery, University Hospital, Umeå, Sweden, Institute of Neurology, University College London, London, United Kingdom(Swepub:umu)hama0032
(author)
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Linköpings universitetBiomedicinsk instrumentteknik
(creator_code:org_t)
Related titles
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In:Stereotactic and Functional Neurosurgery: S. Karger85:6, s. 279-2861011-61251423-0372
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