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Assessment of mucos...
Assessment of mucosal immunity to HIV-1
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- Jespers, Vicky (author)
- Institute for Tropical Medicine, Antwerp, Belgium
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- Harandi, Ali M (author)
- University of Gothenburg
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- Hinkula, Jorma (author)
- Linköpings universitet,Molekylär virologi,Hälsouniversitetet
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- Medaglini, Donata (author)
- University of Siena
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- Le Grand, Roger (author)
- DSV iMETI
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- Stahl-Hennig, Christiane (author)
- German Primate Centre
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- Bogers, Willy (author)
- Biomed Primate Research Centre
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- El Habib, Raphaelle (author)
- Sanofi Pasteur
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- Wegmann, Frank (author)
- University of Oxford
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- Fraser, Carol (author)
- St Georges University London
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- Cranage, Martin (author)
- St Georges University London
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- J Shattock, Robin (author)
- Karolinska University Hospital
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- Spetz, AL (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2014-01-09
- 2010
- English.
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In: EXPERT REVIEW OF VACCINES. - : Expert Reviews. - 1476-0584 .- 1744-8395. ; 9:4, s. 381-394
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
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- A key gap in the development and evaluation of HIV-1 vaccines is insufficient knowledge with regard to sampling techniques and assessment of mucosal immune responses required for early prevention and inhibition of viral dissemination. In an attempt to start bridging this gap, the EUROPRISE network of scientists working on HIV-1 vaccine and microbicide research organized a workshop with the aim to review the types of mucosal responses/biomarkers currently measured in mucosal immunology and to define how the mucosal responses/biomarkers are measured and/or the assays and sampling methods used. The Workshop addressed two critical questions: first whether, with current knowledge, it would be possible to define a consensus set of mucosal sampling methods to facilitate cross-species comparisons and ensure standardized implementation in clinical trials; second to determine the remaining challenges (technical and logistical) and their possible solutions for assessing mucosal responses to HIV-1 vaccines.
Keyword
- assessment
- HIV vaccines
- humans
- macaques
- mice
- mucosal immunity
- rabbits
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Jespers, Vicky
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Harandi, Ali M
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Hinkula, Jorma
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Medaglini, Donat ...
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Le Grand, Roger
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Stahl-Hennig, Ch ...
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show more...
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Bogers, Willy
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El Habib, Raphae ...
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Wegmann, Frank
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Fraser, Carol
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Cranage, Martin
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J Shattock, Robi ...
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Spetz, AL
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show less...
- Articles in the publication
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EXPERT REVIEW OF ...
- By the university
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Linköping University
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Karolinska Institutet