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Aligned carbon nanotubes on quartz substrate for liquid gated biosensing

Palaniappan, AL (author)
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore
Goh, W.H (author)
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore
Tey, J.N. (author)
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore
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Wijaya, I.P.M. (author)
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore
Moochhala, S.M. (author)
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore, DSO National Laboratories, 27 Meidical Drive, Singapore 117510, Singapore; Centre for Biomimetic Sensor Science, 50 Nanyang Drive, Singapore 637553, Singapore
Liedberg, Bo, 1954- (author)
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore, DSO National Laboratories, 27 Meidical Drive, Singapore 117510, Singapore; Centre for Biomimetic Sensor Science, 50 Nanyang Drive, Singapore 637553, Singapore,Molecular Physics
Mhaisalkar, S.G. (author)
School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore, DSO National Laboratories, 27 Meidical Drive, Singapore 117510, Singapore; Centre for Biomimetic Sensor Science, 50 Nanyang Drive, Singapore 637553, Singapore
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School of Materials Science and Engineering Nanyang Technological University, Singapore 639798, Singapore School of Materials Science and Engineering. Nanyang Technological University, Singapore 639798, Singapore, DSO National Laboratories, 27 Meidical Drive, Singapore 117510, Singapore; Centre for Biomimetic Sensor Science, 50 Nanyang Drive, Singapore 637553, Singapore (creator_code:org_t)
Elsevier, 2010
2010
English.
In: Biosensors and Bioelectronics. - : Elsevier. - 0956-5663. ; 25, s. 1989-1993
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • A facile and high performance biosensing platform using aligned carbon nanotubes on quaratz substrate is reported in this communication. Single walled carbon nanotubes are grown on quartz substrates by a chemical vapor despotition process and are characterized with field emission scanning electron microscopy and atomic force microscopy in order to verify the quality of the material. The quartz substrate is then directly used as a biosensor in a field effect transistor configuration. In order to demonstrate the sensing capabilities of the fabricated sensor devices, electronic detection of prostate specific antigen, a potential cancer biomarker, is carried out by adopting liquid gated configuration. A conductivity change due to the specific binding of target antigen with the immobilized receptor andtibody demonstrates the sensing capabilities of the fabricated device. Sub-nM detection sensitivities have been obtained using the adopted direct immunoassay approach, which shows that the device responds to clinically relevant concentration regimes

Subject headings

NATURVETENSKAP  -- Kemi -- Analytisk kemi (hsv//swe)
NATURAL SCIENCES  -- Chemical Sciences -- Analytical Chemistry (hsv//eng)

Keyword

Biosensor. Single walled carbon nanotube. Field effect transistor. Liquid gating
Analytical chemistry
Analytisk kemi

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