Sökning: onr:"swepub:oai:DiVA.org:liu-56805" > Shaping up a lineag...
Fältnamn | Indikatorer | Metadata |
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000 | 03345naa a2200397 4500 | |
001 | oai:DiVA.org:liu-56805 | |
003 | SwePub | |
008 | 100604s2010 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:f8234616-e1fe-4c7a-a2f8-ed7586d34830 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-568052 URI |
024 | 7 | a https://doi.org/10.1016/j.coi.2010.02.0012 DOI |
024 | 7 | a https://lup.lub.lu.se/record/15825082 URI |
040 | a (SwePub)liud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a for2 swepub-publicationtype |
100 | 1 | a Bryder, Davidu Lund University,Lunds universitet,Immunologi,Forskargrupper vid Lunds universitet,Immunology,Lund University Research Groups4 aut0 (Swepub:lu)med-dbr |
245 | 1 0 | a Shaping up a lineage-lessons from B lymphopoesis |
264 | 1 | b Elsevier Science B.V., Amsterdam.c 2010 |
338 | a print2 rdacarrier | |
520 | a Even though the development of B lymphoid cells from hematopoietic stem cells is one of the most carefully investigated models of cell differentiation in adult mammalians, a set of recent findings has to a large extent increased our understanding for how B lymphoid commitment is achieved. These include the identification of IKAROS, PU.1 and E2A as transcription factors responsible for lymphoid lineage priming in multipotent cells, as well as the identification of EBF1 dependent B lineage restricted progenitors among cells lacking expression of the classical B lineage markers CD19 or 8220. The insight that the B cell identity may be defined at an earlier stage then previously thought, allows for an increased understanding of B lymphoid development likely to unravel molecular mechanisms of high relevance also for other differentiation processes within as well as outside of the hematopoietic system. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Sigvardsson, Mikaelu Lund University,Lunds universitet,Linköpings universitet,Experimentell hematologi,Hälsouniversitetet,Stamcellscentrum (SCC),Avdelningen för stamcellsforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Stem Cell Center,Division of stem cell research,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)stem-msi |
710 | 2 | a Immunologib Forskargrupper vid Lunds universitet4 org |
773 | 0 | t CURRENT OPINION IN IMMUNOLOGYd : Elsevier Science B.V., Amsterdam.g 22:2, s. 148-153q 22:2<148-153x 0952-7915x 1879-0372 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/20207528?dopt=Abstracty FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1016/j.coi.2010.02.001y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-56805 |
856 | 4 8 | u https://doi.org/10.1016/j.coi.2010.02.001 |
856 | 4 8 | u https://lup.lub.lu.se/record/1582508 |
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