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A catalytic surface...
A catalytic surface for amyloid fibril formation
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- Hammarström, Per (author)
- Linköpings universitet,Biokemi,Tekniska högskolan
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- Ali Malik, Muhammad (author)
- Linköpings universitet,Institutionen för fysik, kemi och biologi,Tekniska högskolan
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- Mishra, Rajesh (author)
- Linköpings universitet,Biokemi,Tekniska högskolan
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- Svensson, Samuel (author)
- Linköpings universitet,Farmakologi,Hälsouniversitetet
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- Tengvall, Pentti (author)
- Linköpings universitet,Tillämpad Fysik,Tekniska högskolan
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- Lundström, Ingemar (author)
- Linköpings universitet,Tillämpad Fysik,Tekniska högskolan
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(creator_code:org_t)
- 2008-03-27
- 2008
- English.
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In: Journal of Physics, Conference Series. - : Institute of Physics (IoP). - 1742-6588 .- 1742-6596. ; 100
- Related links:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- A hydrophobic surface incubated in a solution of protein molecules (insulin monomers) was made into a catalytic surface for amyloid fibril formation by repeatedly incubate, rinse and dry the surface. The present contribution describes how this unexpected transformation occurred and its relation to rapid fibrillation of insulin solutions in contact with the surface. A tentative model of the properties of the catalytic surface is given, corroborated by ellipsometric measurements of the thickness of the organic layer on the surface and by atomic force microscopy. The surfaces used were spontaneously oxidized silicon made hydrophobic through treatment in dichlorodimethylsilane.
Keyword
- TECHNOLOGY
- TEKNIKVETENSKAP
Publication and Content Type
- ref (subject category)
- art (subject category)
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