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On the Correlation Between DVH Parameters and Linear Penalties in Optimization of HDR Prostate Brachytherapy Dose Plans

Holm, Åsa (author)
Linköpings universitet,Matematiska institutionen,Tekniska högskolan
Larsson, Torbjörn (author)
Linköpings universitet,Optimeringslära,Tekniska högskolan
Carlsson Tedgren, Åsa (author)
Östergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Hälsouniversitetet,Radiofysikavdelningen US
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English.
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  • When optimizing dwell times for HDR brachytherapy it is common to use a model comprising an objective of linear penalties. However whether a planis considered good or not depends on other measures such as DVH-based parameters. We show through experiments that the correlation between the value of the objective function and the values of DVH-based parameters, such as D90, is weak in some cases. It seems that the objective function can only classify solutions into better or worse, however it can not distinguish the best with respect to DVH-based parameters.

Subject headings

NATURVETENSKAP  -- Matematik (hsv//swe)
NATURAL SCIENCES  -- Mathematics (hsv//eng)

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MATHEMATICS
MATEMATIK

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Holm, Åsa
Larsson, Torbjör ...
Carlsson Tedgren ...
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NATURAL SCIENCES
NATURAL SCIENCES
and Mathematics
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Linköping University

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