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  • Rakowski, TomaszJagiellonian University, Krakow, Poland (author)

Impact of infarct related artery patency after early abciximab administration on one-year mortality in patients with ST-segment elevation myocardial infarction (data from the EUROTRANSFER Registry)

  • Article/chapterEnglish2012

Publisher, publication year, extent ...

  • Polskie Towarzystwo Kardiologiczne,2012
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-78589
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-78589URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding Agencies|Eli Lilly and Company, Critical Care Europe, Geneva, Switzerland||Eli Lilly and Company||
  • Background: Spontaneous early infarct related artery (IRA) recanalisation before primary percutaneous coronary intervention (pPCI) has a favourable impact on outcome. However, the role played by pharmacotherapy driven patency prior to pPCI is still a matter of debate. less thanbrgreater than less thanbrgreater thanAim: To assess the role of early IRA patency (TIMI flow 2 or 3) after early abciximab administration in patients with ST-segment elevation myocardial infarction (STEM!) transferred for pPCI. less thanbrgreater than less thanbrgreater thanMethods: Data was gathered for 1,650 consecutive sTEMI patients transferred for pPCI from hospital networks in seven countries in Europe between November 2005 and January 2007. We identified 691 patients who were pretreated with abciximab before transportation to a cathlab hospital and underwent PCI. less thanbrgreater than less thanbrgreater thanResults: Angiography showed early IRA patency (TIMI flow 2 or 3) in 233 (33.7%) patients, and occluded IRA (TIMI flow 0 or 1) in 458 (66.3%) patients. In patients with patent IRA, in baseline angiography the rate of TIMI 3 flow and ECG ST-segment resolution andgt; 50% after PCI was higher compared to patients with occluded IRA. One year mortality was significantly lower in patients with patent IRA, 1.3% vs 7% (OR 0.17; CI 0.05-0.6; p = 0.001). In multivariable Cox regression analysis, IRA patency at baseline was identified as an independent predictor of one-year mortality. less thanbrgreater than less thanbrgreater thanConclusions: Infarct related artery recanalisation after early pharmacological pretreatment in STEMI patients undergoing transportation for pPCI is associated with better post-procedural myocardial perfusion and lower one-year mortality.

Subject headings and genre

  • myocardial infarction
  • angioplasty
  • abciximab
  • reperfusion
  • registries
  • MEDICINE
  • MEDICIN

Added entries (persons, corporate bodies, meetings, titles ...)

  • Siudak, ZbigniewJagiellonian University, Krakow, Poland (author)
  • Dziewierz, ArturJagiellonian University, Krakow, Poland (author)
  • Birkemeyer, RalfSchwarzwald-Baar Klinikum, Villingen-Schwenningen, Germany (author)
  • Janzon, MagnusÖstergötlands Läns Landsting,Linköpings universitet,Kardiologi,Hälsouniversitetet,Kardiologiska kliniken US(Swepub:liu)magja75 (author)
  • Mielecki, WaldemarJagiellonian University, Krakow, Poland (author)
  • Zmudka, KrzysztofJagiellonian University, Krakow, Poland (author)
  • S Dubiel, JacekJagiellonian University, Krakow, Poland (author)
  • Dudek, DariuszJagiellonian University, Krakow, Poland (author)
  • Jagiellonian University, Krakow, PolandSchwarzwald-Baar Klinikum, Villingen-Schwenningen, Germany (creator_code:org_t)

Related titles

  • In:Kardiologia polska: Polskie Towarzystwo Kardiologiczne70:3, s. 215-2210022-90321897-4279

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