Search: onr:"swepub:oai:DiVA.org:liu-79206" >
Breast cancer risk ...
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Lundell, MarieKarolinska Institutet
(author)
Breast cancer risk after radiotherapy in infancy : a pooled analysis of two Swedish cohorts of 17,202 infants
- Article/chapterEnglish1999
Publisher, publication year, extent ...
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Radiation Research Society,1999
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-79206
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-79206URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:15688132URI
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https://doi.org/10.2307/3580039DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The incidence of breast cancer was studied in a cohort of 17,202 women irradiated for skin hemangioma in infancy at the Radiumhemmet, Stockholm, or the Sahlgrenska University Hospital, Gothenburg. A major part of the cohort had been treated with radium-226 applicators, and the mean absorbed dose to the breasts was 0.29 Gy (range <0.01-35.8 Gy). Two hundred forty-five breast cancers were diagnosed in the cohort during the period 1958-1993, and the standardized incidence ratio (SIR) was 1.20 (95% CI 1.06-1.36). Different dose-response models were tested, and a linear model gave the best fit. Neither age at exposure, breast dose rate, ovarian dose nor time since exposure had any statistically significant modifying effect, and breast dose was the only determinant of risk. The excess relative risk per gray (ERR/Gy) was 0.35 (95% CI 0.18-0.59), which is lower than in most other studies.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Mattsson, AndersRadiumhemmet, Karolinska Hospital, Stockholm
(author)
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Karlsson, PerSahlgrenska University Hospital, Gothenburg
(author)
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Holmberg, ErikSahlgrenska University Hospital, Gothenburg
(author)
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Gustafsson, Agnetha,1960-Sahlgrenska University Hospital, Gothenburg(Swepub:liu)agngu51
(author)
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Holm, Lars-ErikSwedish Radiation Protection Institute, Solna
(author)
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Karolinska InstitutetRadiumhemmet, Karolinska Hospital, Stockholm
(creator_code:org_t)
Related titles
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In:Radiation Research: Radiation Research Society151:5, s. 626-6320033-75871938-5404
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