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Intranasal versus i...
Intranasal versus intravenous administration of midazolam to children undergoing small bowel biopsy
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- Högberg, Lotta (author)
- Östergötlands Läns Landsting
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- Nordvall, M. (author)
- Östergötlands Läns Landsting
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- Tjellström, L. (author)
- Östergötlands Läns Landsting
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- Stenhammar, Lars (author)
- Östergötlands Läns Landsting
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(creator_code:org_t)
- Wiley, 1995
- 1995
- English.
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In: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 84:12, s. 1429-1431
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Sixty-three children under the age of 9 years were randomized to receive intravenous (group A, n= 33) or intranasal (group B, n= 30) midazolam as sedation for small bowel biopsy. Mean doses of midazolam given to produce adequate sedation were 0.31 mg (kg body weight)−1 in group A and 0.34 mg (kg body weight)−1 in group B (NS). Four children in group A and 10 children in group B required additional doses to maintain adequate sedation throughout the biopsy procedure (p <0.05). There was no significant difference between the groups regarding the median procedure time (7 min in group A, 8.5 min in group B) or median fluoroscopy time (5 s in group A, 4 s in group B). All children in group B showed signs of discomfort from the nose when given midazolam intranasally. In conclusion, this study indicates that intravenous administration of midazolam is preferable to the intranasal route.
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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