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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003505naa a2200493 4500
001oai:DiVA.org:liu-87007
003SwePub
008130108s2003 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-870072 URI
024a https://doi.org/10.1016/S1359-6446(02)02563-12 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Los, Marek Janu Institute of Experimental Dermatology, University of Muenster, Germany4 aut0 (Swepub:liu)marlo14
2451 0a Anticancer drugs of tomorrow :b apoptotic pathways as targets for drug design
264 1b Elsevier,c 2003
338 a electronic2 rdacarrier
520 a Apoptosis or programmed cell death is a set of ordered events that enables the selective removal of cells from tissue and is essential for homeostasis and proper function of multicellular organisms. Components of this signaling network, which include ligands, such as CD95, tumor necrosis factor (TNF) and TNF-related apoptosis-inducing ligand, as well as downstream molecules, such as caspases, Bcl-2 family members, and inhibitor-of-apoptosis proteins, which trigger and regulate apoptosis, are crucial targets for conventional drug development and gene therapy of cancer and other diseases. Here, we focus on apoptotic pathways and propose new potential molecular targets that could prove effective in controlling cell death in the clinical setting.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Medicinsk bioteknologi0 (SwePub)304012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Medical Biotechnology0 (SwePub)304012 hsv//eng
653 a bcl-2 protein family
653 a caspase activation
653 a cytochrome-c
653 a interleukin-1-beta converting-enzyme
653 a leukemia-cells
653 a mice deficient
653 a programmed cell-death
653 a serine-protease
653 a structural basis
653 a trail-induced apoptosis
700a Burek, C. J.u Institute of Experimental Dermatology, University of Muenster, Germany4 aut
700a Stroh, C.u Institute of Experimental Dermatology, University of Muenster, Germany4 aut
700a Benedyk, K.u Dept of Tumor Biology Oncology Center, Maria Sklodowska-Curie Memorial Institute, Wybrzeze Armii Krajowej 15, PL-44100 Gliwice, Poland4 aut
700a Hug, H.u TheraSTrat AGGewerbestrasse 25, CH-4123, Allschwil, Switzerland4 aut
700a Mackiewicz, A.u Dept of Cancer Immunology, University of Medical Sciences, at Great-Poland Cancer Center, Poznan, Poland4 aut
710a Institute of Experimental Dermatology, University of Muenster, Germanyb Dept of Tumor Biology Oncology Center, Maria Sklodowska-Curie Memorial Institute, Wybrzeze Armii Krajowej 15, PL-44100 Gliwice, Poland4 org
773t Drug Discovery Todayd : Elsevierg 8:2, s. 67-77q 8:2<67-77x 1359-6446x 1878-5832
856u https://liu.diva-portal.org/smash/get/diva2:584216/FULLTEXT01.pdfx primaryx Raw objecty fulltext:preprint
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-87007
8564 8u https://doi.org/10.1016/S1359-6446(02)02563-1

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By the author/editor
Los, Marek Jan
Burek, C. J.
Stroh, C.
Benedyk, K.
Hug, H.
Mackiewicz, A.
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Cancer and Oncol ...
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Medical Biotechn ...
and Medical Biotechn ...
Articles in the publication
Drug Discovery T ...
By the university
Linköping University

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