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Ratiometric tempera...
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Ye, FangmaoDepartment of Chemistry, University of Washington, Seattle, USA
(author)
Ratiometric temperature sensing with semiconducting polymer dots
- Article/chapterEnglish2011
Publisher, publication year, extent ...
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2011-05-11
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American Chemical Society (ACS),2011
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-90567
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-90567URI
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https://doi.org/10.1021/ja202945gDOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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This communication describes ultrabright single-nanoparticle ratiometric temperature sensors based on semiconducting polymer dots (Pdots). We attached the temperature sensitive dye—Rhodamine B (RhB), whose emission intensity decreases with increasing temperature—within the matrix of Pdots. The as-prepared Pdot-RhB nanoparticle showed excellent temperature sensitivity and high brightness because it took advantage of the light harvesting and amplified energy transfer capability of Pdots. More importantly, the Pdot-RhB nanoparticle showed ratiometric temperature sensing under a single wavelength excitation and has a linear temperature sensing range that matches well with the physiologically relevant temperatures. We employed Pdot-RhB for measuring intracellular temperatures in a live-cell imaging mode. The exceptional brightness of Pdot-RhB allows this nanoscale temperature sensor to be used also as a fluorescent probe for cellular imaging.
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Wu, ChangfengDepartment of Chemistry, University of Washington, Seattle, USA
(author)
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Jin, YuhuiDepartment of Chemistry, University of Washington, Seattle, USA
(author)
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Chan, Yang-HsiangDepartment of Chemistry, University of Washington, Seattle, USA
(author)
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Zhang, XuanjunDepartment of Chemistry, University of Washington, Seattle, USA(Swepub:liu)xuazh91
(author)
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Chiu, Daniel TDepartment of Chemistry, University of Washington, Seattle, USA
(author)
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Department of Chemistry, University of Washington, Seattle, USA
(creator_code:org_t)
Related titles
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In:Journal of the American Chemical Society: American Chemical Society (ACS)133:21, s. 8146-81490002-78631520-5126
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