A child with a long-standing, intensely itching subcutaneous nodule on a thigh: an uncommon (?) reaction to commonly used vaccines

Bergfors, ElisabetÖstergötlands Läns Landsting,Linköpings universitet,Institutionen för medicin och hälsa,Hälsouniversitetet,Forsknings- och utvecklingsenheten för Närsjukvården i Östergötland (author)

A child with a long-standing, intensely itching subcutaneous nodule on a thigh : an uncommon (?) reaction to commonly used vaccines

A 2-year-old girl presented with an intensely itching subcutaneous nodule on the front of a thigh. The nodule persisted for 10 months until it was excised. Subsequent investigation for malignancy and systemic disease showed no pathological findings. The diagnosis, persistent itching vaccination granuloma, was revealed by hazard almost 2 years after the onset of symptoms. Persistent itching subcutaneous nodules at the injection site for aluminium containing vaccines (mostly diphtheria-tetanus-pertussis combination vaccines for primary immunisation of infants) may appear with a long delay after the vaccination (months), cause prolonged itching (years) and are often associated with contact allergy to aluminium. The condition is poorly recognised in Health Care which may lead to prolonged symptoms and unnecessary investigations.

Lundmark, KatarzynaÖstergötlands Läns Landsting,Linköpings universitet,Avdelningen för inflammationsmedicin,Hälsouniversitetet,Klinisk patologi och klinisk genetik(Swepub:liu)katlu09 (author)
Nyström Kronander, UllaÖstergötlands Läns Landsting,Linköpings universitet,Allergicentrum,Hälsouniversitetet,Allergicentrum US(Swepub:liu)ullny16 (author)
Linköpings universitetInstitutionen för medicin och hälsa (creator_code:org_t)

By the author/editor: Bergfors, Elisab ...; Lundmark, Katarz ...; Nyström Kronande ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Pediatrics

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Dermatology and ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and General Practice

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