Search: onr:"swepub:oai:DiVA.org:liu-98192" >
Preoperative Topica...
Preoperative Topical Hypothermia used in Prolonged Severe Lower Limb Ischemia to Avoid Ischemic Damage - The First Clinical Experience
-
- Forsell, Claes (author)
- Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet
-
- Åberg, Jonas (author)
- Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet
-
- Szabó, Zoltán (author)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet,Thorax-kärlkliniken i Östergötland
-
(creator_code:org_t)
- 2013
- 2013
- English.
-
In: International Journal of Biomedical Science. - 1550-9702 .- 1555-2810. ; 9:3, s. 181-184
- Related links:
-
http://www.ijbs.org/...
-
show more...
-
https://liu.diva-por... (primary) (Raw object)
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- Severe lower limb ischemia TASC IIB/III with sensory and motor neurologic deficiencies leads to prolonged hospital care, amputation, and death in 20-70 % of cases. We present our first clinical experience of the use of preoperative topical hypothermia to improve muscular viability in these patients. Two hours after onset of symptoms, six 4-liter plastic bags were filled with snow and packed against the ischemic leg which was protected from frost injury by a layer of towels. After surgical revascularization four hours later muscular and neural functions in the leg were completely restored. A maximum serum myoglobin of 6500 ng/L (median 12000 ng/L in similar but untreated patients) postoperatively decreased to 1400 ng/L after 27 hours.
Keyword
- skeletal muscle; topical hypothermia; limb ischemia; ischemic damage; protection
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database