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  • Spyrou, GiannisKarolinska institutet, Stockholm, Sweden (author)

Ribonucleotides are not channeled into DNA in permeabilized mammalian cells

  • Article/chapterEnglish1983

Publisher, publication year, extent ...

  • Elsevier,1983
  • printrdacarrier

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  • LIBRIS-ID:oai:DiVA.org:liu-98741
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-98741URI

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  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Reddy and Pardee earlier reported that permeabilized CHEF/18 cells (J. Biol. Chem 257, 12526) or soluble extracts from such cells (Cell 32, 443) under the proper conditions preferentially incorporated a labeled ribonucleotide (CDP) into DNA without dilution by an excess of non-labeled dCTP, suggesting channeling of ribonucleotides into DNA by a multiprotein complex. Here we present results suggesting that in these experiments CDP was incorporated into RNA and not into DNA.

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  • Reichard, PeterKarolinska institutet, Stockholm, Sweden (author)
  • Karolinska institutet, Stockholm, Sweden (creator_code:org_t)

Related titles

  • In:Biochemical and Biophysical Research Communications - BBRC: Elsevier115:3, s. 1022-10260006-291X1090-2104

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