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Changes of blood vi...
Changes of blood viscosity in pateints treated with 5-fluorouracil : A link to cardiotoxicity?
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- Cwikiel, Magdalena (author)
- Department of Oncology, University Hospital, Lund. Sweden
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- Persson, Sylvi Ulrika (author)
- Department of Internal Medicine, University Hospital, Lund, Sweden
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- Larsson, Hans (author)
- Department of Internal Medicine, University Hospital, Lund, Sweden
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- Albertsson, Maria (author)
- Department of Oncology, University Hospital, Lund. Sweden
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- Eskilsson, Jan (author)
- Department of Cardiology, University Hospital, Lund. Sweden
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Department of Oncology, University Hospital, Lund Sweden Department of Internal Medicine, University Hospital, Lund, Sweden (creator_code:org_t)
- Norway, 1995
- 1995
- English.
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In: Acta Oncologica. - Norway. - 0284-186X .- 1651-226X. ; 34:1, s. 83-85
- Related links:
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https://urn.kb.se/re...
Abstract
Subject headings
Close
- Abstract Cardiotoxicity is a serious but relatively unknown side-effect of treatment with 5-fluorouracil (5-FU). The underlying mechanism of 5-FU cardiotoxicity has not been defined. The aim of the present study was to determine whether hemorheological factors might in part explain 5-FU cardiotoxicity. Changes of blood and plasma viscosity, fibrinogen and hematocrit were studied in 11 patients treated by 5-FU. The study showed a decrease in blood and plasma viscosity during treatment with 5-FU, probably caused by a decrease of plasma fibrinogen. Reversible cardiotoxic effects were demonstrated in four patients.
Keyword
- Cardiotoxicity; Blood viscosity; Fluorouracil; Head and neck neoplasms; Drug therapy
- MEDICINE
- MEDICIN
- Biomedicinsk vetenskap
- Biomedical Sciences
- Vårdvetenskap
- Caring Science
Publication and Content Type
- ref (subject category)
- art (subject category)
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