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Depression was asso...
Depression was associated with younger age, female sex, obesity, smoking, and physical inactivity, in 1027 patients with newly diagnosed type 2 diabetes : a Swedish multicentre cross-sectional study
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- Melin, Eva O. (author)
- Lund University,Lunds universitet,Diabetes lab,Forskargrupper vid Lunds universitet,Lund University Research Groups,Region Kronoberg,Skåne University Hospital
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- Wanby, Pär (author)
- Linnaeus University,Linköpings universitet,Linnéuniversitetet,Institutionen för medicin och optometri (MEO),Linköping University, Sweden;Region Kalmar County, Sweden,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Linnaeus Univ, Sweden; Kalmar Cty Hosp, Sweden,Kalmar County Hospital
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- Neumark, Thomas (author)
- Regional Executive Office ‑ Coordination of Health Care Kalmar, Sweden;Region Kalmar County, Sweden,Reg Execut Off Coordinat Hlth Care, Sweden; Dept Res, Sweden
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- Holmberg, Sara (author)
- Linnaeus University,Lund University,Lunds universitet,Linnéuniversitetet,Institutionen för medicin och optometri (MEO),Region Kronoberg, Sweden;Lund University, Sweden,Reg Kronoberg, Sweden; Linnaeus Univ, Sweden; Lund Univ, Sweden,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Miljöepidemiologi,Forskargrupper vid Lunds universitet,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Environmental Epidemiology,Lund University Research Groups
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- Neumark, Ann-Sofi Nilsson (author)
- Region Kalmar County, Sweden;Primary Care Mönsterås, Sweden,Dept Res, Sweden; Primary Care, Sweden
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- Johansson, Karin (author)
- Linnaeus University,Linnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV),Region Kronoberg, Sweden,Reg Kronoberg, Sweden; Reg Kronoberg, Sweden; Linnaeus Univ, Sweden
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- Landin-Olsson, Mona (author)
- Lund University,Lunds universitet,Diabetes lab,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital
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- Thulesius, Hans (author)
- Linnaeus University,Lund University,Lunds universitet,Linnéuniversitetet,Institutionen för medicin och optometri (MEO),Region Kronoberg, Sweden;Lund University, Sweden,Reg Kronoberg, Sweden; Reg Kronoberg, Sweden; Linnaeus Univ, Sweden; Lund Univ, Sweden,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups
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- Hillman, Magnus (author)
- Lund University,Lunds universitet,Diabetes lab,Forskargrupper vid Lunds universitet,Lund University Research Groups
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- Thunander, Maria (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Växjö Central Hospital,Region Kronoberg
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(creator_code:org_t)
- 2022-11-09
- 2022
- English.
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In: BMC Endocrine Disorders. - : BioMed Central (BMC). - 1472-6823. ; 22:1
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Abstract
Subject headings
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- Background Depression is a risk factor for type 2 diabetes (T2D) and cardiovascular disease (CVD). The aims were to explore the prevalence of depression, anxiety, antidepressant use, obesity, Hemoglobin A1c > 64 mmol/mol, life-style factors, pre-existing CVD, in patients with newly diagnosed T2D; to explore associations with depression; and to compare with Swedish general population data. Methods Multicentre, cross-sectional study. Inclusion criteria: adults with serologically verified newly diagnosed T2D. Included variables: age, sex, current depression and anxiety (Hospital Anxiety and Depression Scale), previous depression, antidepressant use, obesity (BMI >= 30 and >= 40 kg/m(2)), Hemoglobin A1c, pre-existing CVD. Logistic regression analyses were performed. Results In 1027 T2D patients, aged 18-94 years, depression was associated with age (per year) (inversely) (odds ratio (OR) 0.97), anxiety (OR 12.2), previous depression (OR 7.1), antidepressant use (OR 4.2), BMI >= 30 kg/m(2) (OR 1.7), BMI >= 40 kg/m(2) (OR 2.3), smoking (OR 1.9), physical inactivity (OR 1.8), and women (OR 1.6) (all p <= 0.013). Younger women (n = 113), <= 59 years, compared to younger men (n = 217) had higher prevalence of current depression (31% vs 12%), previous depression (43 vs 19%), anxiety (42% vs 25%), antidepressant use (37% vs 12%), BMI >= 30 kg/m(2) (73% vs 60%) and BMI >= 40 kg/m(2)) (18% vs 9%), and smoking (26% vs 16%) (all p <= 0.029). Older women (n = 297), >= 60 years, compared to older men (n = 400) had higher prevalence of previous depression (45% vs 12%), anxiety (18% vs 10%), antidepressant use (20% vs 8%), BMI >= 30 kg/m(2) (55% vs 47%), BMI >= 40 kg/m(2) (7% vs 3%) (all p <= 0.048), but not of current depression (both 9%). Compared to the Swedish general population (depression (women 11.2%, men 12.3%) and antidepressant use (women 9.8%, men 5.3%)), the younger women had higher prevalence of current depression, and all patients had higher prevalence of antidepressant use. Conclusions In patients with newly diagnosed T2D, the younger women had the highest prevalence of depression, anxiety, and obesity. The prevalence of depression in young women and antidepressant use in all patients were higher than in the Swedish general population. Three risk factors for CVD, obesity, smoking, and physical inactivity, were associated with depression.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Age
- Antidepressants
- Anxiety
- Depression
- Epidemiology
- Obesity
- Physical inactivity
- Sex differences
- Smoking
- Type 2 diabetes
- Health and Caring Sciences
- Hälsovetenskap
- Medicin
- Medicine
- Age
- Antidepressants
- Anxiety
- Depression
- Epidemiology
- Obesity
- Physical inactivity
- Sex differences
- Smoking
- Type 2 diabetes
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Melin, Eva O.
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Wanby, Pär
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Neumark, Thomas
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Holmberg, Sara
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Neumark, Ann-Sof ...
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Johansson, Karin
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Landin-Olsson, M ...
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Thulesius, Hans
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Hillman, Magnus
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Thunander, Maria
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Psychiatry
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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BMC Endocrine Di ...
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Linnaeus University
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Linköping University
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Lund University