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Experimental Assess...
Experimental Assessment of the Environmental Fate and Effects of Triazoles and Benzotriazole
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- Durjava, Mojca Kos (author)
- Publ Hlth Inst Maribor, Slovenia
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- Kolar, Boris (author)
- Publ Hlth Inst Maribor, Slovenia
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- Arnus, Lovro (author)
- Publ Hlth Inst Maribor, Slovenia
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- Papa, Ester (author)
- Univ Insubria, Italy
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- Kovarich, Simona (author)
- Univ Insubria, Italy
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- Sahlin, Ullrika (author)
- Linnéuniversitetet,Institutionen för biologi och miljö (BOM)
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- Peijnenburg, Willie (author)
- Natl Inst Publ Hlth & Environm RIVM, Netherlands ; Leiden Univ, Netherlands
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(creator_code:org_t)
- 2013-03-01
- 2013
- English.
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In: ATLA (Alternatives to Laboratory Animals). - : SAGE Publications. - 0261-1929. ; 41:1, s. 65-75
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- The environmental fate and effects of triazoles and benzotriazoles are of concern within the context of chemical regulation. As part of an intelligent testing strategy, experimental tests were performed on endpoints that are relevant for risk assessment. The experimental tests included the assessment of eco-toxicity to an alga, a daphnid and zebrafish embryos, and the assessment of ready biodegradability. Triazole and benzotriazole compounds were selected for testing, based on existing toxicity data for vertebrate and invertebrate species, as well as on the principal component analysis of molecular descriptors aimed at selecting the minimum number of test compounds in order to maximise the chemical domain spanned for both compound classes. The experimental results show that variation in the toxicities of triazoles and benzotriazole across species was relatively minor; in general, the largest factor was approximately 20. The study conducted indicated that triazoles are not readily biodegradable.
Subject headings
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
Keyword
- algae
- aquatic toxicity
- benzotriazoles
- daphnids
- ready biodegradability
- triazoles
- zebrafish embryos
- Miljövetenskap
- Environmental Science
Publication and Content Type
- ref (subject category)
- art (subject category)
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