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  • Ricci, S.Univ Roma La Sapienza, Italy (author)

Altered Cytokine and BDNF Levels in Autism Spectrum Disorder

  • Article/chapterEnglish2013

Publisher, publication year, extent ...

  • 2013-04-19
  • Springer,2013
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:lnu-70987
  • https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-70987URI
  • https://doi.org/10.1007/s12640-013-9393-4DOI
  • https://gup.ub.gu.se/publication/189564URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • The contribution of neuroimmune functioning and brain-derived neurotrophic factor (BDNF) to functional dysregulation in autism spectrum disorder was assessed in 29 patients under treatment in two specialized centers of Basilicata (Chiaromonte and Matera), Southern Italy, through analysis of serum levels of cytokines and BDNF. Elevated levels of the pro-inflammatory cytokine, including interleukin-1, interleukin-6, interleukin-12, interleukin-23, tumor necrosis factor-alpha and BDNF were observed, regardless of age and gender. Comparisons were made with age-and gender-related healthy controls. The present findings reinforce current notions regarding immunoexcitotoxic mechanisms contributing to the pathophysiology of autistic disorder.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Businaro, R.Sapienza Univ, Italy (author)
  • Ippoliti, F.Univ Roma La Sapienza, Italy (author)
  • Lo Vasco, V. R.Univ Roma La Sapienza, Italy (author)
  • Massoni, F.Univ Roma La Sapienza, Italy (author)
  • Onofri, E.Univ Roma La Sapienza, Italy (author)
  • Troili, G. M.Univ Roma La Sapienza, Italy (author)
  • Pontecorvi, V.Sapienza Univ, Italy (author)
  • Morelli, M.Sapienza Univ, Italy (author)
  • Rapp-Ricciardi, Max,1964University of Gothenburg(Swepub:gu)xrapma (author)
  • Archer, TrevorGothenburg University,Göteborgs universitet,Linnéuniversitetet,Institutionen för idrottsvetenskap (ID),University of Gothenburg,Psykologiska institutionen,Department of Psychology(Swepub:gu)xarctr (author)
  • Univ Roma La Sapienza, ItalySapienza Univ, Italy (creator_code:org_t)

Related titles

  • In:Neurotoxicity research: Springer24:4, s. 491-5011029-84281476-3524

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