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Exercise Reduces Sa...
Exercise Reduces Salivary Morning Cortisol Levels in Patients with Depression
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- Rahman, M. S. (author)
- Karolinska Institutet, Sweden
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- Zhao, X. (author)
- Karolinska Institutet, Sweden
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- Liu, J. J. (author)
- Karolinska Institutet, Sweden;Karolinska University Hospital, Sweden
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- Torres, E. Q. (author)
- Karolinska Institutet, Sweden
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- Tibert, B. (author)
- Karolinska Institutet, Sweden;Karolinska University Hospital, Sweden
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- Kumar, P. (author)
- Karolinska Institutet
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- Kaldo, Viktor (author)
- Linnéuniversitetet,Institutionen för psykologi (PSY),Karolinska Institutet, Sweden,DISA
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- Lindefors, N. (author)
- Karolinska Institutet
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- Forsell, Y. (author)
- Karolinska Institutet
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- Lavebratt, C. (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2018-12-19
- 2019
- English.
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In: Molecular Neuropsychiatry. - : S. Karger. - 2296-9209 .- 2296-9179. ; 4:4, s. 196-203
- Related links:
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https://doi.org/10.1...
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https://www.karger.c...
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https://urn.kb.se/re...
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Abstract
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- Purpose of the Study: Cortisol hypersecretion plays a role in depression pathophysiology. Internet-based cognitive behavioural therapy (ICBT) and physical exercise (PE) are new treatment alternatives for depression, and their long-lasting effect on cortisol is unknown. We investigated cortisol level changes after 12 weeks of ICBT, PE or treatment as usual (TAU).Procedures: The present pre-post repeated measure study analysed data derived from a randomised controlled trial evaluating the effects of 12 weeks’ interventions of ICBT, PE and TAU in depressed primary care patients (Sweden 2011–2013) and aimed at prospectively evaluating the within-group effects of ICBT, PE and TAU on diurnal salivary cortisol levels in a small representative subsample (n = 56, 38 and 27, respectively).Results: We found a marked flattening of the diurnal cortisol slope (p = 0.004) and a reduced cortisol level at awakening (p = 0.017) after 12 weeks of PE treatment. No apparent effects of ICBT or TAU interventions were seen on diurnal cortisol levels.Conclusions and Message: PE reduced the rate of cortisol level decline across the day in depressed adults. ICBT and TAU treatments had no detectable effects on diurnal cortisol levels. Larger samples are required for the detection and comparison of smaller effects of PE, ICBT and TAU on diurnal cortisol levels.
Subject headings
- SAMHÄLLSVETENSKAP -- Psykologi -- Tillämpad psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology -- Applied Psychology (hsv//eng)
Keyword
- Psychology
- Psykologi
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Rahman, M. S.
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Zhao, X.
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Liu, J. J.
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Torres, E. Q.
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Tibert, B.
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Kumar, P.
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Kaldo, Viktor
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Lindefors, N.
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Forsell, Y.
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Lavebratt, C.
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- About the subject
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Psychology
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and Applied Psycholo ...
- Articles in the publication
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Molecular Neurop ...
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Complex Psychiat ...
- By the university
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Linnaeus University
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Karolinska Institutet