onr:"swepub:oai:DiVA.org:mau-15399"
Search: onr:"swepub:oai:DiVA.org:mau-15399" > Cytokines in health...
- 1 of 1
- Previous record
- Next record
- To hitlist
- Kristensen, KD (author)
Cytokines in healthy temporomandibular joint synovial fluid
- Article/chapterEnglish2014
Publisher, publication year, extent ...
- 2014-02-27
- John Wiley & Sons,2014
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:mau-15399
- https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-15399URI
- https://doi.org/10.1111/joor.12146DOI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Analysis of temporomandibular joint (TMJ) synovial fluid may elucidate the aetiology of temporomandibular disorders and arthritic conditions, as well as the inflammatory mechanisms involved. Knowledge about healthy synovial fluid is necessary to understand TMJ pathologies. We aimed to quantify the proinflammatory cytokines interleukin (IL)-1β, IL-2, IL-6 and tumour necrosis factor (TNF), and the anti-inflammatory cytokines IL-10 and interferon (IFN)-γ in healthy TMJ synovial fluid to serve as reference values for future studies on TMJ pathologies. Twenty healthy, young adult volunteers without temporomandibular dysfunction were included. Bilateral synovial fluid samples were obtained using the push-pull technique with hydroxocobalamin described by Alstergren in 1999. Cytokines were quantified with Luminex multiplex assays and compared using nonparametric statistical analysis. No serious adverse effects were reported. Of 40 possible samples, 14 fulfilled the strict sampling criteria and were included in the analysis. Cytokine values (reported as medians with interquartile ranges) were as follows: TNF, 23 (13-37) pg mL(-1) ; IL-2, 1·8 (0-22) pg mL(-1) ; and INF-γ, 10 (0-47) pg mL(-1) . IL-1β, IL-6 and IL-10 were almost undetectable. In addition, TNF and INF-γ cytokine levels correlated. We demonstrated that TNF was consistently detected and IFN-γ and IL-2 sporadically detected in the TMJ synovial fluid of healthy individuals using the hydroxocobalamin method and a multiplex assay. The cytokines IL-10, IL-1β and IL-6 were barely detectable in this sample of healthy TMJs
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
- Alstergren, PerMalmö högskola,Odontologiska fakulteten (OD)(Swepub:mau)odpeal (author)
- Stoustrop, P (author)
- Kuseler, A (author)
- Herlin, T (author)
- Pedersen, TK (author)
- Malmö högskolaOdontologiska fakulteten (OD) (creator_code:org_t)
Related titles
- In:Journal of Oral Rehabilitation: John Wiley & Sons41:4, s. 250-2561365-28420305-182X
Internet link
Find in a library
- Journal of Oral Rehabilitation (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Kristensen, KD
- Alstergren, Per
- Stoustrop, P
- Kuseler, A
- Herlin, T
- Pedersen, TK
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Dentistry
- Articles in the publication
- Journal of Oral ...
- By the university
- Malmö University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
