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Dental pulp capping :
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Olsson, HelenaMalmö högskola,Odontologiska fakulteten (OD)
(author)
Dental pulp capping : effect of Emdogain Gel on experimentally exposed human pulps
- Article/chapterEnglish2005
Publisher, publication year, extent ...
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John Wiley & Sons,2005
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Numbers
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LIBRIS-ID:oai:DiVA.org:mau-15846
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https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-15846URI
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https://doi.org/10.1111/j.1365-2591.2004.00932.xDOI
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https://lup.lub.lu.se/record/135233URI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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AIM: To investigate the effect of Emdogain Gel (Biora AB, Malmo, Sweden), consisting of a enamel matrix derivative (EMD) in a propylene glycol alginate (PGA) vehicle, on experimentally exposed human pulps and to register postoperative symptoms. METHODOLOGY: Nine pairs of contralateral premolars scheduled for extraction on orthodontic indications were included. Following a superficial pulp amputation performed with a small (016) diamond bur, either EMDgel or a mix of calcium hydroxide and sterile saline was placed at random in contact with the pulp wound. The subjects made records of symptoms and were also interviewed about pain/discomfort by a blinded examiner. After 12 weeks the teeth were extracted, prepared and subjected to light microscopic examination in which the inflammation and newly formed hard tissue in the pulp were analysed. Immunohistochemistry was performed using affinity-purified rabbit anti-EMD polyclonal antibodies. RESULTS: Postoperative symptoms were less frequent in the EMDgel-treated than in the calcium hydroxide-treated teeth, especially during the first six weeks. In the EMDgel-treated teeth, new tissue partly filled the space initially occupied by the gel and hard tissue was formed alongside the exposed dentine surfaces and in patches in the adjacent pulp tissue. EMD was detected in the areas where new hard tissue had been formed. The wound area of the EMDgel-treated teeth exhibited inflammation in the majority of the teeth whereas less inflammation was seen in the calcium hydroxide-treated teeth where the hard tissue was formed as a bridge. CONCLUSIONS: In the EMDgel-treated teeth, postoperative symptoms were less frequent and the amount and pattern of hard tissue formation were markedly different than in the teeth treated with calcium hydroxide. However, the operative procedure and the formulation with EMD in a PGA vehicle do not seem to be effective for the formation of a hard tissue barrier.
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Added entries (persons, corporate bodies, meetings, titles ...)
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Davies, JuliaMalmö högskola,Odontologiska fakulteten (OD)(Swepub:mau)odjuda
(author)
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Holst, KE
(author)
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Schröder, UllaMalmö högskola,Odontologiska fakulteten (OD)
(author)
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Petersson, KerstinMalmö högskola,Odontologiska fakulteten (OD)(Swepub:mau)odkepe
(author)
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Lindkvist, KarinLund University,Lunds universitet,Institutionen för experimentell medicinsk vetenskap,Medicinska fakulteten,Department of Experimental Medical Science,Faculty of Medicine(Swepub:lu)mbfy-kpe
(author)
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Malmö högskolaOdontologiska fakulteten (OD)
(creator_code:org_t)
Related titles
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In:International Endodontic Journal: John Wiley & Sons38:3, s. 186-1940143-28851365-2591
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