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Peripheral giant ce...
Peripheral giant cell granuloma : an updated analysis of 2824 cases reported in the literature
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- Chrcanovic, Bruno (author)
- Malmö universitet,Odontologiska fakulteten (OD)
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- Cavalieri Gomes, Carolina (author)
- Department of Pathology, Biological Sciences Institute, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
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- Santiago Gomez, Ricardo (author)
- Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
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(creator_code:org_t)
- 2018-04-10
- 2018
- English.
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In: Journal of Oral Pathology & Medicine. - : John Wiley & Sons. - 0904-2512 .- 1600-0714. ; 47:5, s. 454-459
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Abstract
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- Objective. To integrate the available data published on peripheral giant cell granuloma (PGCG) into a comprehensive analysis of its clinical/radiologic features. Materials and Methods. An electronic search was undertaken in January/2018 in 5 databases, looking for publications reporting cases of PGCGs. Probability of recurrence was calculated for some variables. Results. 165 publications were included, 2824 lesions identified. PGCGs were slightly more prevalent in women and more prevalent in mandibles, usually asymptomatic, and presenting erosion of the subjacent bone in almost 1/3 of cases. Additional curettage (2.8%) or peripheral osteotomy (0%) after excision presented lower recurrence rates in comparison to excision alone (16%). Excision followed by curettage decreases the probability of recurrence by 85% in comparison to excision alone. Other factors (age, lesion size, follow-up, gender, location, clinical symptoms, bone erosion) seem to do not influence the probability of recurrence. Conclusions. As surgical excision alone shows a considerable recurrence rate, excision followed by an additional therapy - curettage or peripheral osteotomy - should be the first choice of treatment of PGCG.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Keyword
- Peripheral giant cell granuloma
- Giant cell lesion
- Clinical features
- Treatment
- Recurrence rate
Publication and Content Type
- ref (subject category)
- for (subject category)
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