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Antibodies Against ...
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Pendleton, HilleviLund University,Lunds universitet,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups
(author)
Antibodies Against Gonadotropin-Releasing Hormone in Patients with Posterior Laryngitis
- Article/chapterEnglish2013
Publisher, publication year, extent ...
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Libertas Academica,2013
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electronicrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:mau-4189
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https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-4189URI
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https://doi.org/10.4137/DTI.S10837DOI
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https://lup.lub.lu.se/record/3559909URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Patients with functional gastrointestinal disorders express antibodies against gonadotropin-releasing hormone (GnRH) in serum. One common cause of posterior laryngitis (PL) is extra-esophageal reflux, but a functional etiology has also been suggested. The aim of this study was to scrutinize patients with PL with regard to the presence of GnRH antibodies and to examine the association between antibodies and symptoms and reflux. Consecutive PL patients were included after examination. Serum was analyzed for the presence of antibodies using an enzyme-linked immunosorbent assay (ELISA) method and expressed as relative units (RU). Two age- and gender-matched healthy subjects per case served as controls. The prevalence of IgM GnRH antibodies in patients was 35% compared with 28% in controls (P = 0.06), with higher levels in patients (0.8 (0.3-2.2) RU) than in controls (0.2 (0.1-0.6) RU) (P = 0.007). The corresponding IgG antibody prevalences were 43% and 4%, respectively (P = 0.001), with no difference in levels (P = 0.70). There was no association between antibodies and clinical findings
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Alm, RagnarLund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups(Swepub:lu)medf-ral
(author)
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Nordin Fredrikson, GunillaLund University,Lunds universitet,Malmö högskola,Institutionen för biomedicinsk vetenskap (BMV),Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups(Swepub:lu)medf-gno
(author)
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Ohlsson, BodilLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups(Swepub:lu)kir-boh
(author)
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Laryngoesofagologi, allergi och livskvalitetForskargrupper vid Lunds universitet
(creator_code:org_t)
Related titles
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In:Drug Target Insights: Libertas Academica:7, s. 1-81177-3928
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