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Lipidomic “Deep Pro...
Lipidomic “Deep Profiling” : An Enhanced Workflow to Reveal New Molecular Species of Signaling Lipids
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Narayanaswamy, Pradeep (author)
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- Shinde, Sudhirkumar (author)
- Malmö högskola,Institutionen för biomedicinsk vetenskap (BMV)
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Sulc, Robert (author)
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Kraut, Rachel (author)
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Staples, Gregory (author)
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Thiam, Chung Hwee (author)
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Grimm, Rudolf (author)
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- Sellergren, Börje (author)
- Malmö högskola,Institutionen för biomedicinsk vetenskap (BMV)
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Torta, Federico (author)
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Wenk, Markus R. (author)
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(creator_code:org_t)
- 2014-02-27
- 2014
- English.
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In: Analytical Chemistry. - : American Chemical Society (ACS). - 0003-2700 .- 1520-6882. ; 86:6, s. 3043-3047
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Current mass spectrometry-based lipidomics aims to comprehensively cover wide ranges of lipid classes. We introduce a strategy to capture phospho-monoester lipids and improve the detection of long-chain base phosphates (LCB-Ps, e.g., sphingosine-1-phosphate). Ten novel LCB-Ps (d18:2, t20:1, odd carbon forms) were discovered and characterized in tissues from human and mouse, as well in D. melanogaster and S. cerevisiae. These findings have immediate relevance for our understanding of sphingosine-1-phosphate biosynthesis, signaling, and degradation.
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Narayanaswamy, P ...
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Shinde, Sudhirku ...
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Sulc, Robert
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Kraut, Rachel
-
Staples, Gregory
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Thiam, Chung Hwe ...
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show more...
-
Grimm, Rudolf
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Sellergren, Börj ...
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Torta, Federico
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Wenk, Markus R.
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show less...
- Articles in the publication
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Analytical Chemi ...
- By the university
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Malmö University