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  • Gudmundsson, PetriMalmö högskola,Fakulteten för hälsa och samhälle (HS) (author)

Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT

  • Article/chapterEnglish2009

Publisher, publication year, extent ...

  • 2009-04-20
  • BioMed Central,2009
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:mau-4511
  • https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-4511URI
  • https://doi.org/10.1186/1476-7120-7-19DOI
  • https://lup.lub.lu.se/record/1444040URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:118849893URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Background: Real-time perfusion (RTP) contrast echocardiography can be used during adenosine stress echocardiography (ASE) to evaluate myocardial ischemia. We compared two different types of RTP power modulation techniques, angiomode (AM) and high-resolution grayscale (HR), with 99mTc-tetrofosmin single-photon emission computed tomography (SPECT) for the detection of myocardial ischemia. Methods: Patients with known or suspected coronary artery disease (CAD), admitted to SPECT, were prospectively invited to participate. Patients underwent RTP imaging (SONOS 5500) using AM and HR during Sonovue® infusion, before and throughout the adenosine stress, also used for SPECT. Analysis of myocardial perfusion and wall motion by RTP-ASE were done for AM and HR at different time points, blinded to one another and to SPECT. Each segment was attributed to one of the three main coronary vessel areas of interest. Results: In 50 patients, 150 coronary areas were analyzed by SPECT and RTP-ASE AM and HR. SPECT showed evidence of ischemia in 13 out of 50 patients. There was no significant difference between AM and HR in detecting ischemia (p = 0.08). The agreement for AM and HR, compared to SPECT, was 93% and 96%, with Kappa values of 0.67 and 0.75, respectively (p < 0.001). Conclusion: There was no significant difference between AM and HR in correctly detecting myocardial ischemia as judged by SPECT. This suggests that different types of RTP modalities give comparable data during RTP-ASE in patients with known or suspected CAD.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Shahgaldi, Kambiz (author)
  • Winter, ReidarKarolinska Institutet (author)
  • Dencker, MagnusLund University,Lunds universitet,Klinisk fysiologi och nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Physiology and Nuclear Medicine, Malmö,Lund University Research Groups(Swepub:lu)klin-mde (author)
  • Kitlinski, MariuszLund University,Lunds universitet,Obstetrisk, gynekologisk och prenatal ultraljudsdiagnostik,Forskargrupper vid Lunds universitet,Obstetric, Gynaecological and Prenatal Ultrasound Research,Lund University Research Groups(Swepub:lu)med-mzk (author)
  • Thorsson, OlaLund University,Lunds universitet,Klinisk fysiologi och nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Physiology and Nuclear Medicine, Malmö,Lund University Research Groups(Swepub:lu)klin-oth (author)
  • Ljunggren, LennartMalmö högskola,Fakulteten för hälsa och samhälle (HS)(Swepub:mau)hslelj (author)
  • Willenheimer, RonnieLund University,Lunds universitet,Kardiologiska klinikens forskargrupp,Forskargrupper vid Lunds universitet,Cardiology Research Group,Lund University Research Groups(Swepub:lu)medf-rw0 (author)
  • Malmö högskolaFakulteten för hälsa och samhälle (HS) (creator_code:org_t)

Related titles

  • In:Cardiovascular Ultrasound: BioMed Central7:191476-7120

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