Search: onr:"swepub:oai:DiVA.org:mau-959" > Biomaterials for pr...
Fältnamn | Indikatorer | Metadata |
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000 | 03802naa a2200373 4500 | |
001 | oai:DiVA.org:mau-959 | |
003 | SwePub | |
008 | 200227s2015 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-9592 URI |
024 | 7 | a https://doi.org/10.1111/prd.120862 DOI |
040 | a (SwePub)mau | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a for2 swepub-publicationtype |
100 | 1 | a Sculean, Anton4 aut |
245 | 1 0 | a Biomaterials for promoting periodontal regeneration in human intrabony defects :b a systematic review |
264 | c 2015-04-13 | |
264 | 1 | b John Wiley & Sons,c 2015 |
338 | a electronic2 rdacarrier | |
520 | a Intrabony periodontal defects are a frequent complication of periodontitis and, if left untreated, may negatively affect long-term tooth prognosis. The optimal outcome of treatment in intrabony defects is considered to be the absence of bleeding on probing, the presence of shallow pockets associated with periodontal regeneration (i.e. formation of new root cementum with functionally orientated inserting periodontal ligament fibers connected to new alveolar bone) and no soft-tissue recession. A plethora of different surgical techniques, often including implantation of various types of bone graft and/or bone substitutes, root surface demineralization, guided tissue regeneration, growth and differentiation factors, enamel matrix proteins or various combinations thereof, have been employed to achieve periodontal regeneration. Despite positive observations in animal models and successful outcomes reported for many of the available regenerative techniques and materials in patients, including histologic reports, robust information on the degree to which reported clinical improvements reflect true periodontal regeneration does not exist. Thus, the aim of this review was to summarize, in a systematic manner, the available histologic evidence on the effect of reconstructive periodontal surgery using various types of biomaterials to enhance periodontal wound healing/regeneration in human intrabony defects. In addition, the inherent problems associated with performing human histologic studies and in interpreting the results, as well as certain ethical considerations, are discussed. The results of the present systematic review indicate that periodontal regeneration in human intrabony defects can be achieved to a variable extent using a range of methods and materials. Periodontal regeneration has been observed following the use of a variety of bone grafts and substitutes, guided tissue regeneration, biological factors and combinations thereof. Combination approaches appear to provide the best outcomes, whilst implantation of alloplastic material alone demonstrated limited, to no, periodontal regeneration. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng |
700 | 1 | a Nikolidakis, Dimitris4 aut |
700 | 1 | a Nikou, George4 aut |
700 | 1 | a Ivanovic, Aleksandar4 aut |
700 | 1 | a L.C. Chapple, Ian4 aut |
700 | 1 | a Stavropoulos, Andreasu Malmö högskola,Odontologiska fakulteten (OD)4 aut0 (Swepub:mau)ac3062 |
710 | 2 | a Malmö högskolab Odontologiska fakulteten (OD)4 org |
773 | 0 | t Periodontology 2000d : John Wiley & Sonsg 68:1, s. 182-216q 68:1<182-216x 0906-6713x 1600-0757 |
856 | 4 | u https://mau.diva-portal.org/smash/get/diva2:1397640/FULLTEXT01.pdfx primaryx Raw objecty fulltext:postprint |
856 | 4 | u https://mau.diva-portal.org/smash/get/diva2:1397640/FULLTEXT01.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-959 |
856 | 4 8 | u https://doi.org/10.1111/prd.12086 |
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