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Factors and Situati...
Factors and Situations Affecting the Value of Patient Preference Studies : Semi-Structured Interviews in Europe and the US
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- Whichello, Chiara (author)
- Erasmus School of Health Policy & Management and Erasmus Choice Modelling Centre, Erasmus University, Rotterdam, Netherlands
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- van Overbeeke, Eline (author)
- Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium
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- Janssens, Rosanne (author)
- Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium
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- Schölin Bywall, Karin (author)
- Uppsala universitet,Centrum för forsknings- och bioetik
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- Russo, Selena (author)
- 4Applied Research Division for Cognitive and Psychological Science, IEO European Institute of Oncology IRCCS, Milan, Italy
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- Weldwijk, Jorien (author)
- Erasmus School of Health Policy & Management and Erasmus Choice Modelling Centre, Erasmus University, Rotterdam, Netherlands
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- Cleemput, Irina (author)
- Belgian Health Care Knowledge Centre, Brussels, Belgium
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- Juhaeri, Juhaeri (author)
- Sanofi, Bridgewater, NJ, United States,Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany
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- Levitan, Bennet (author)
- Global R&D Epidemiology, Janssen Research & Development, Titusville, United States
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- Kübler, Jürgen (author)
- Quantitative Scientific Consulting, Marburg, Germany
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- Smith, Meredith (author)
- Global Patient Safety and Labeling, Amgen Inc., Thousand Oaks, CA, United States
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- Hermann, Richard (author)
- Astra Zeneca, Gaithersburg, MD, United States
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- Engelbrecht, Matthias (author)
- Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany
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- Heuber, Alex J. (author)
- Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany
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- Comanescu, Alina (author)
- Community Health Association, Bucharest, Romania
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- Harding, Sarah (author)
- Global Patient Safety, Takeda, London, United Kingdom
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- Simoens, Steven (author)
- Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium
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- Huys, Isabelle (author)
- Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium
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- de Bekker-Grob, Esther (author)
- Erasmus School of Health Policy & Management and Erasmus Choice Modelling Centre, Erasmus University, Rotterdam, Netherlands
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(creator_code:org_t)
- 2019-09-18
- 2019
- English.
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In: Frontiers in Pharmacology. - : Frontiers Media S.A.. - 1663-9812. ; 10
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Objectives: Patient preference information (PPI) is gaining recognition among the pharmaceutical industry, regulatory authorities, and health technology assessment (HTA) bodies/payers for use in assessments and decision-making along the medical product lifecycle (MPLC). This study aimed to identify factors and situations that influence the value of patient preference studies (PPS) in decision-making along the MPLC according to different stakeholders.Methods: Semi-structured interviews (n = 143) were conducted with six different stakeholder groups (physicians, academics, industry representatives, regulators, HTA/payer representatives, and a combined group of patients, caregivers, and patient representatives) from seven European countries (the United Kingdom, Sweden, Italy, Romania, Germany, France, and the Netherlands) and the United States. Framework analysis was performed using NVivo 11 software.Results: Fifteen factors affecting the value of PPS in the MPLC were identified. These are related to: study organization (expertise, financial resources, study duration, ethics and good practices, patient centeredness), study design (examining patient and/or other preferences, ensuring representativeness, matching method to research question, matching method to MPLC stage, validity and reliability, cognitive burden, patient education, attribute development), and study conduct (patients’ ability/willingness to participate and preference heterogeneity). Three types of situations affecting the use of PPS results were identified (stakeholder acceptance, market situations, and clinical situations).Conclusion: The factors and situation types affecting the value of PPS, as identified in this study, need to be considered when designing and conducting PPS in order to promote the integration of PPI into decision-making along the MPLC.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)
Keyword
- patient preferences
- drug life cycle
- decision-making
- health technology assessment
- benefit risk assessment
- market authorization
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Whichello, Chiar ...
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van Overbeeke, E ...
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Janssens, Rosann ...
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Schölin Bywall, ...
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Russo, Selena
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Weldwijk, Jorien
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show more...
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Cleemput, Irina
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Juhaeri, Juhaeri
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Levitan, Bennet
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Kübler, Jürgen
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Smith, Meredith
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Hermann, Richard
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Engelbrecht, Mat ...
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Heuber, Alex J.
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Comanescu, Alina
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Harding, Sarah
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Simoens, Steven
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Huys, Isabelle
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de Bekker-Grob, ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Social and Clini ...
- Articles in the publication
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Frontiers in Pha ...
- By the university
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Mälardalen University
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Uppsala University