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Motion detection and correction for dynamic: 15O-water myocardial perfusion PET studies
- Naum, Alexandru (author)
-
- Laaksonen, Marko (author)
- Mittuniversitetet,Institutionen för hälsovetenskap (-2013)
- Tuunanen, Helena (author)
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- Oikonen, Vesa (author)
- Teräs, Mika (author)
- Kemppainen, Jukka (author)
- Järvisalo, Mikko (author)
- Nuutilja, Pirjo (author)
- Knuuti, Juhani (author)
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- (creator_code:org_t)
- 2005-09-03
- 2005
- English.
- In: European Journal of Nuclear Medicine and Molecular Imaging. - : Springer Science and Business Media LLC. - 1619-7070 .- 1619-7089. ; 32:12, s. 1378-1383
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Patient motion during dynamic PET studies is a well-documented source of errors. The purpose of this study was to investigate the incidence of frame-to-frame motion in dynamic ( 15)O-water myocardial perfusion PET studies, to test the efficacy of motion correction methods and to study whether implementation of motion correction would have an impact on the perfusion results. We tested manual, in-house-developed motion correction software and an automatic motion correction using a rigid body point model implemented in MIPAV (Medical Image Processing, Analysis and Visualisation) software. At rest, patient motion was found in 18% of the frames, but during pharmacological stress the fraction increased to 45% and during physical exercise it rose to 80%. Both motion correction algorithms significantly decreased (p<0.006) the number of moved frames and the amplitude of motion (p<0.04). Motion correction significantly increased MBF results during bicycle exercise (p<0.02). Applying motion correction for the data acquired during exercise clearly changed the MBF results, indicating that motion correction is required for these studies.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Idrottsvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Sport and Fitness Sciences (hsv//eng)
Keyword
- PET
- myocardial blood flow
- motion detection
- motion correction
- physical exercise
- Sports
- Idrott
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Naum, Alexandru
- Laaksonen, Marko
- Tuunanen, Helena
- Oikonen, Vesa
- Teräs, Mika
- Kemppainen, Jukk ...
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- Järvisalo, Mikko
- Nuutilja, Pirjo
- Knuuti, Juhani
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
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- Mid Sweden University
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