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X-ray deconvolution...
X-ray deconvolution microscopy
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- Ehn, Sebastian (author)
- Tech Univ Munich, Phys Dept, Lehrstuhl Biomed Phys, James Franck Str, D-85748 Garching, Germany
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- Epple, Franz Michael (author)
- Tech Univ Munich, Phys Dept, Lehrstuhl Biomed Phys, James Franck Str, D-85748 Garching, Germany
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- Fehringer, Andreas (author)
- Tech Univ Munich, Phys Dept, Lehrstuhl Biomed Phys, James Franck Str, D-85748 Garching, Germany
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- Pennicard, David (author)
- Deutsch Elektronen Synchrotron DESY, Notkestr 85, D-22607 Hamburg, Germany
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- Graafsma, Heinz (author)
- Mittuniversitetet,Avdelningen för elektronikkonstruktion,Deutsch Elektronen Synchrotron DESY, Notkestr 85, D-22607 Hamburg, Germany
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- Noel, Peter (author)
- Tech Univ Munich, Phys Dept, Lehrstuhl Biomed Phys, James Franck Str, D-85748 Garching, Germany
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- Pfeiffer, Franz (author)
- Tech Univ Munich, Phys Dept, Lehrstuhl Biomed Phys, James Franck Str, D-85748 Garching, Germany
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(creator_code:org_t)
- 2016
- 2016
- English.
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In: Biomedical Optics Express. - 2156-7085. ; 7:4, s. 1227-1239
- Related links:
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https://doi.org/10.1...
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https://miun.diva-po... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Recent advances in single-photon-counting detectors are enabling the development of novel approaches to reach micrometer-scale resolution in x-ray imaging. One example of such a technology are the MEDIPIX3RX-based detectors, such as the LAMBDA which can be operated with a small pixel size in combination with real-time on-chip charge-sharing correction. This characteristic results in a close to ideal, box-like point spread function which we made use of in this study. The proposed method is based on raster-scanning the sample with sub-pixel sized steps in front of the detector. Subsequently, a deconvolution algorithm is employed to compensate for blurring introduced by the overlap of pixels with a well defined point spread function during the raster-scanning. The presented approach utilizes standard laboratory x-ray equipment while we report resolutions close to 10 mu m. The achieved resolution is shown to follow the relationship p/n with the pixel-size p of the detector and the number of raster-scanning steps n. (C) 2016 Optical Society of America
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Elektroteknik och elektronik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Electrical Engineering, Electronic Engineering, Information Engineering (hsv//eng)
- NATURVETENSKAP -- Fysik -- Acceleratorfysik och instrumentering (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Accelerator Physics and Instrumentation (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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