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- Schreya, A (author)
Functional evaluation of microvascular free flaps with positron emission tomography
- Article/chapterEnglish2006
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- Elsevier BV,2006
- printrdacarrier
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- LIBRIS-ID:oai:DiVA.org:miun-3718
- https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-3718URI
- https://doi.org/10.1016/j.bjps.2005.04.016DOI
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- Language:English
- Summary in:English
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- BACKGROUND: The aim of this study was to assess blood flow (BF) of microvascular free flaps studied with positron emission tomography (PET) in patients with head and neck squamous cell cancer (HNSCC) undergoing major radical surgery 3-4 weeks after high-dose radiotherapy. METHODS: Five patients underwent resection of the HNSCC of the oral cavity followed by microvascular reconstruction with a radial forearm flap. Regional BF in oral and neck tissues was measured with PET using radiolabelled water ([(15)O]H(2)O) twice (1-2 and 12-14 days, respectively) following radical surgery. RESULTS: In the first postoperative PET study, the median BF in the cutaneous flap area was 5.1mL/100g/min, and in the muscle contra-lateral to the recipient site 19.9mL/100g/min. A low flap-to-muscle BF ratio appeared to correlate with circulatory incongruity, and thus with poorer flap success. The follow-up study on the second postoperative week supported the results of the primary PET scan. CONCLUSIONS: This pilot study suggests that PET using [(15)O]H(2)O is a feasible method to quantitatively evaluate BF of the whole free flap in patients operated on for oral HNSCC.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Idrottsvetenskap hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences Sport and Fitness Sciences hsv//eng
- PET
- free flaps
- blood flow
- postoperative
- head and neck cancer
- Idrottsvetenskap
- MEDICINE
- MEDICIN
- Sports
- Idrott
Added entries (persons, corporate bodies, meetings, titles ...)
- Aitasalo, KMJ (author)
- Kinnunen, IAJ, (author)
- Laaksonen, MarkoMittuniversitetet,Institutionen för hälsovetenskap (-2013)(Swepub:miun)marlaa (author)
- Parkkola, RK (author)
- Taittonen, MT (author)
- Grenman, RA (author)
- Minn, H R I (author)
- MittuniversitetetInstitutionen för hälsovetenskap (-2013) (creator_code:org_t)
Related titles
- In:Journal of Plastic, reconstructive & Aesthetic Surgery: Elsevier BV59:2, s. 158-1651748-6815
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- Grenman, RA
- Minn, H R I
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