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COVID‐19 and myasthenia gravis : A review of neurological implications of the SARS‐COV‐2

Shah, Syed Muhammad Ismail (author)
Department of Internal Medicine Ziauddin Medical University Karachi Pakistan
Yasmin, Farah (author)
Department of Internal Medicine, Dow Medical College Dow University of Health Sciences Karachi Pakistan
Memon, Roha Saeed (author)
Department of Internal Medicine, Dow Medical College Dow University of Health Sciences Karachi Pakistan
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Jatoi, Nadia Nazir (author)
Department of Internal Medicine, Dow Medical College Dow University of Health Sciences Karachi Pakistan
Savul, Ilma Saleh (author)
Department of Internal Medicine St. Joseph Medical Center Houston Texas USA
Kazmi, Sana (author)
Department of Internal Medicine, Dow Medical College Dow University of Health Sciences Karachi Pakistan
Monawwer, Syed Abdullah (author)
Department of Internal Medicine Ziauddin Medical University Karachi Pakistan
Zafar, Muhammad Daim Bin (author)
Department of Internal Medicine, Dow Medical College Dow University of Health Sciences Karachi Pakistan
Asghar, Muhammad Sohaib (author)
Department of Internal Medicine Dow University Ojha Hospital Karachi Pakistan
Tahir, Muhammad Junaid (author)
Lahore General Hospital Lahore Pakistan
Lee, Ka Yiu (author)
Mittuniversitetet,Institutionen för hälsovetenskaper (HOV),Swedish Winter Sports Research Centre
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 (creator_code:org_t)
2022-10-28
2022
English.
In: Brain and Behavior. - : Wiley. - 2162-3279 .- 2162-3279. ; 12:12
  • Research review (peer-reviewed)
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  • IntroductionThis review highlights the potential mechanisms of neuromuscular manifestation of COVID-19, especially myasthenia gravis (MG).MethodsAn extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020.ResultsExacerbations of clinical symptoms in patients of MG who were treated with some commonly used COVID-19 drugs has been reported, with updated recommendations of management of symptoms of neuromuscular disorders. Severe acute respiratory syndrome coronavirus 2 can induce the immune response to trigger autoimmune neurological disorders.ConclusionsFurther clinical studies are warranted to indicate and rather confirm if MG in the setting of COVID-19 can pre-existent subclinically or develop as a new-onset disease.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)

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