Search: onr:"swepub:oai:DiVA.org:oru-107290" >
Changes in prevalen...
Changes in prevalence of non-optimal neurological condition between 6.5 and 12 years in children born extremely preterm
-
- Nosko, Daniela, 1986- (author)
- Paediatric Department, Örebro University Hospital, Örebro, Sweden,Orebro Univ Hosp, Sweden
-
- Broström, Lina (author)
- Neonatal Research Unit, Department of Women’s and Children’s Health, Karolinska Institute, Stockholm, Sweden; Sachs’ Children and Youth Hospital, Stockholm, Sweden,Karolinska Inst, Sweden; Sachs Children & Youth Hosp, Sweden
-
- Bolk, Jenny (author)
- Karolinska Institutet
-
show more...
-
- Ådén, Ulrika (author)
- Karolinska Institutet,Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Karolinska Inst, Sweden
-
- Örtqvist, Maria (author)
- Karolinska Institutet
-
show less...
-
(creator_code:org_t)
- Elsevier, 2023
- 2023
- English.
-
In: European journal of paediatric neurology. - : Elsevier. - 1090-3798 .- 1532-2130. ; 45, s. 14-18
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Aim: To assess prevalence of non-optimal neurological condition and associations with motor function in children born extremely preterm (EPT) up to early adolescence, and to examine potential changes in neurological con-dition between 6.5 and 12 years.Method: A prospective cohort of one hundred six children (EPT n = 62, term n = 44) was assessed at 6.5 and 12 years. Four domains derived from the Touwen Neurological Examination (coordination and balance, posture and muscle tone, reflexes, and nerve function of the eyes and face) were used to assess the presence of a non-optimal neurological condition (defined as the presence of any abnormal domain). The Movement Assessment Battery for Children 2nd ed. was used to evaluate motor function.Results: Twenty-seven children born EPT (44%) were assessed as having a non-optimal neurological condition compared with 4 (9%) in the control group (p=<0.001) at 12 years. Between age 6.5 and 12 years the number of children born EPT with a non-optimal neurological condition decreased from 37 to 27 (p = 0.007). At 12 years these children also had significantly lower MABC-2 total test scores, compared to those with normal neurology: median (range) 57 (32-79) versus 75 (43-99), respectively (p=<0.001). The same was shown for subscale scores; manual dexterity (p=<0.001), aiming/catching (p = 0.004), and balance (p = 0.004).Conclusion: The prevalence of a non-optimal neurological condition reduced with increasing age. However, still, at 12 years, these neurological impairments remained significantly more common in the EPT group than in their term-born peers and was shown to be related to a reduced motor function.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- Extremely preterm
- Neurodevelopment
- Neurological dysfunction
- Prevalence
- Motor function
- Minor neurological dysfunction
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database