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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006207naa a2200529 4500
001oai:DiVA.org:oru-107815
003SwePub
008230824s2023 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:153522682
009oai:DiVA.org:liu-201632
024a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-1078152 URI
024a https://doi.org/10.1111/apt.176752 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1535226822 URI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2016322 URI
040 a (SwePub)orud (SwePub)kid (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Everhov, Åsa H.u Karolinska Institutet,Department of Clinical Science and Education, Södersjukhuset Karolinska Institutet Stockholm Sweden;Clinical Epidemiology Division, Department of Medicine Solna Karolinska Institutet Stockholm Sweden4 aut
2451 0a Increasing healthcare costs in inflammatory bowel disease 2007-2020 in Sweden
264 1b John Wiley & Sons,c 2023
338 a print2 rdacarrier
500 a Funding agency:Kommunfullmäktige, Stockholms stad Dnr 20190638
520 a BACKGROUND: Inflammatory bowel disease has been linked to increasing healthcare costs, but longitudinal data on other societal costs are scarce.AIM: To assess costs, including productivity losses, in patients with prevalent Crohn's disease (CD) or ulcerative colitis (UC) in Sweden between 2007 and 2020.METHODS: We linked data from national registers on all patients with CD or UC and a matched (sex, birthyear, healthcare region and education) reference population. We assessed mean costs/year in Euros, inflation-adjusted to 2020, for hospitalisations, out-patient visits, medications, sick leave and disability pension. We defined excess costs as the mean difference between patients and matched comparators.RESULTS: Between 2007 and 2020, absolute mean annual societal costs in working-age (18-64 years) individuals decreased by 17% in CD (-24% in the comparators) and by 20% in UC (-27% in comparators), due to decreasing costs from sick leave and disability, a consequence of stricter sick leave regulations. Excess costs in 2007 were dominated by productivity losses. In 2020, excess costs were mostly healthcare costs. Absolute and excess costs increased in paediatric and elderly patients. Overall, costs for TNF inhibitors/targeted therapies increased by 274% in CD and 638% in UC, and the proportion treated increased from 5% to 26% in CD, and from 1% to 10% in UC.CONCLUSION: Between 2007 and 2020, excess costs shifted from productivity losses to direct healthcare costs; that is, the patients' compensation for sickness absence decreased, while society increased its spending on medications. Medication costs were driven both by expanding use of TNF inhibitors and by high costs for newer targeted therapies.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi0 (SwePub)303012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Health Care Service and Management, Health Policy and Services and Health Economy0 (SwePub)303012 hsv//eng
700a Söderling, Jonasu Karolinska Institutet,Clinical Epidemiology Division, Department of Medicine Solna Karolinska Institutet Stockholm Sweden4 aut
700a Befrits, Gustafu Region Stockholm, Stockholm, Sweden4 aut
700a Khalili, Hamedu Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA4 aut
700a Bröms, Gabriellau Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Gastroenterology Unit, Danderyd Hospital, Stockholm, Sweden4 aut
700a Neovius, Martinu Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 aut
700a Askling, Johanu Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 aut
700a Halfvarson, Jonas,d 1970-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden4 aut0 (Swepub:oru)jshn
700a Ludvigsson, Jonas F.,d 1969-u Karolinska Institutet,Department Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden;Department of Pediatrics Örebro University Hospital, Örebro University Örebro Sweden4 aut0 (Swepub:oru)jsln
700a Olén, Olau Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Pediatric Gastroenterology and Nutrition, Sachs' Children and Youth Hospital, Stockholm, Sweden4 aut
700a SWIBREG study group, -4 ctb
700a Myrelid, Pär,d 1970-u Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US,SWIBREG study group4 ctb0 (Swepub:liu)parmy24
710a Karolinska Institutetb Department of Clinical Science and Education, Södersjukhuset Karolinska Institutet Stockholm Sweden;Clinical Epidemiology Division, Department of Medicine Solna Karolinska Institutet Stockholm Sweden4 org
773t Alimentary Pharmacology and Therapeuticsd : John Wiley & Sonsg 58:7, s. 692-703q 58:7<692-703x 0269-2813x 1365-2036
856u https://doi.org/10.1111/apt.17675y Fulltext
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-107815
8564 8u https://doi.org/10.1111/apt.17675
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:153522682
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-201632

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