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  • Breedvelt, Josefien J. F.Department of Psychiatry, Amsterdam Public Health (APH), Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands; Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK (author)

An individual participant data meta-analysis of psychological interventions for preventing depression relapse

  • Article/chapterEnglish2024

Publisher, publication year, extent ...

  • 2024
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:oru-111886
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-111886URI
  • https://doi.org/10.1038/s44220-023-00178-xDOI

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  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  •  This project was funded in part by internal funds fromthe Alliance for Public Health at the Amsterdam University MedicalCentre—Mental Health Stream.
  • Major depressive disorder is a leading cause of disability worldwide; identifying effective strategies to prevent depression relapse is crucial. This individual participant data meta-analysis addresses whether and for whom psychological interventions can be recommended for relapse prevention of major depressive disorder. One- and two-stage individual patient data meta-analyses were conducted on 14 randomized controlled trials (N = 1,720). The relapse risk over 12 months was substantially lower for those who received a psychological intervention versus treatment as usual, antidepressant medication, or evaluation-only control (hazard ratio, 0.60; 95% confidence interval, 0.48–0.74). The number of previous depression episodes moderated the treatment effect, with psychological interventions demonstrating greater efficacy for patients with three or more previous episodes. Our results suggest that adding psychological interventions to current treatment to prevent depression relapse is recommended. For patients at lower risk of relapse, less-intensive approaches may be indicated.

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  • Karyotaki, EiriniDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; WHO Collaborating Centre for Research and Dissemination of Psychological Interventions, Vrije Universiteit Amsterdam, Amsterdam, Netherlands (author)
  • Warren, Fiona C.Department of Health and Community Sciences, University of Exeter, Exeter, UK (author)
  • Brouwer, Marlies E.Department of Psychiatry, Amsterdam Public Health (APH), Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands (author)
  • Jermann, FrançoiseDepartment of Psychiatry, Geneva University Hospitals, Geneva, Switzerland (author)
  • Holländare, Fredrik,Docent,1972-Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Psychiatry(Swepub:oru)fhe (author)
  • Klein, NicolaTrauma Center Department, GGZ Drenthe Mental Health Institute, Assen, Netherlands (author)
  • de Jonge, MargoResearch Department, Arkin Mental Health Institute, Amsterdam, Netherlands (author)
  • Klein, Daniel N.Department of Psychology, Stony Brook University, Stony Brook, NY, USA (author)
  • Farb, NormanDepartment of Psychology, University of Toronto Mississauga, Mississauga, Ontario, Canada; Department of Psychological Clinical Science, University of Toronto Scarborough, Toronto, Ontario, Canada (author)
  • Segal, ZindelDepartment of Psychology, University of Toronto Mississauga, Mississauga, Ontario, Canada (author)
  • Biesheuvel Leliefeld, Karolien E. M.Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands (author)
  • Jarrett, RobinDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA (author)
  • Vittengl, JeffreyDepartment of Psychology, Truman State University, Kirksville, MO, USA (author)
  • Thase, MichaelDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA (author)
  • Ma, HelenHong Kong Centre for Mindfulness, Hong Kong, Hong Kong (author)
  • Kuyken, WillemDepartment of Psychiatry, University of Oxford, Oxford, UK (author)
  • Shallcross, Amanda J.Department of Population Health, NYU School of Medicine, New York, NY, USA (author)
  • van Heeringen, CornelisFaculty of Medicine and Health Sciences, Ghent University, Gent, Belgium (author)
  • Hoorelbeke, KristofDepartment of Experimental Clinical and Health Psychology, Ghent University, Gent, Belgium (author)
  • Koster, ErnstDepartment of Experimental Clinical and Health Psychology, Ghent University, Gent, Belgium (author)
  • Williams, MarkDepartment of Psychiatry, University of Oxford, Oxford, UK (author)
  • Huijbers, Marloes J.Department of Psychiatry, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands (author)
  • Speckens, AnneDepartment of Psychiatry, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands (author)
  • Cuijpers, PimDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; WHO Collaborating Centre for Research and Dissemination of Psychological Interventions, Vrije Universiteit Amsterdam, Amsterdam, Netherlands (author)
  • van Oppen, PatriciaDepartment of Research and Innovation, GGZ InGeest Specialized Mental Health Care, Amsterdam, Netherlands; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, APH-Research Institute, Amsterdam, Netherlands (author)
  • Gilbody, SimonYork Mental Health and Addictions Research Group (MHARG), University of York, York, UK (author)
  • Bockting, Claudi L.Department of Psychiatry, Amsterdam Public Health (APH), Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands; Centre for Urban Mental Health, University of Amsterdam, Amsterdam, Netherland (author)
  • Department of Psychiatry, Amsterdam Public Health (APH), Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands; Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UKDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; WHO Collaborating Centre for Research and Dissemination of Psychological Interventions, Vrije Universiteit Amsterdam, Amsterdam, Netherlands (creator_code:org_t)

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  • In:Nature Mental Health2:2, s. 154-1632731-6076

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