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Diabetic retinopathy among the elderly with type 2 diabetes : A Nationwide longitudinal registry study

Sharif, Ali, 1986- (author)
Örebro universitet,Institutionen för medicinska vetenskaper,Department of Ophthalmology, Örebro University Hospital, Örebro, Sweden
Smith, Daniel R., 1981- (author)
Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Clinical Epidemiology and Biostatistics
Hellgren, Karl-Johan, 1971- (author)
Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Ophthalmology, Karlstad Hospital, Karlstad, Sweden
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Jendle, Johan, 1963- (author)
Örebro universitet,Institutionen för medicinska vetenskaper
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 (creator_code:org_t)
2024
2024
English.
In: Acta Ophthalmologica. - : John Wiley & Sons. - 1755-375X .- 1755-3768.
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Purpose: To investigate the prevalence, incidence and risk factors of DR in elderly people living with type 2 diabetes.Methods: Individuals >80 years, in the Swedish National Diabetes Register (NDR) between 2008 and 2017, were included. Prevalence and incidence were calculated and stratified by age. Estimates were assessed by longitudinal binary logistic regression models.Results: One hundred forty-one thousand, one hundred fifty-eight individuals with type 2 diabetes were included, median age 83 years, 53.3% females and with a median HbA1c 52 mmol/mol. The DR prevalence was stable at 336.2 cases/1000 patients in 2008 (95% CI, 330.2-342.3), with no significant changes during the 10-year period. Crude DR incidence rate: 88.5 cases/1000 patient years (95% CI, 87.6-89.4). The incidence rate was lower at higher ages. The effect of age on incident DR varied by sex, with females having an increasingly higher risk than males from 83 years of age, OR 1.25 (1.11-1.42) at age 90 years. The risk of incident DR with longer diabetes duration increased more rapidly at worse glycaemic control.Conclusion: The growing population of elderly with type 2 diabetes shows a stable proportion of DR and proposes an increased need for DR screening and eye care. Established risk factors for DR, such as diabetes duration and level of glycaemic control, are also important in the elderly; however, age and sex should be considered.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Oftalmologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Ophthalmology (hsv//eng)

Keyword

80 years and over
aged
diabetic retinopathy
incidence
prevalence
risk factors

Publication and Content Type

ref (subject category)
art (subject category)

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