Expert opinion on the use of contraception in people with multiple sclerosis

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Expert opinion on the use of contraception in people with multiple sclerosis

Hillert, Jan (author): Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

Bove, Riley (author): UCSF Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA

Haddad, Lisa B. (author): Center for Biomedical Research, Population Council, New York, NY, USA

Hellwig, Kerstin (author): Katholisches Klinikum Bochum GmbH, Nordrhein-Westfalen, Bochum, Germany

Houtchens, Maria (author): Brigham and Women's Hospital, Boston, MA, USA/ Harvard Medical School, Boston, MA, USA

Magyari, Melinda (author): Danish Multiple Sclerosis Center, University Hospital Boston, MA, USA/ Rigshospitalet, Copenhagen, Denmark

Merki-Feld, Gabriele S. (author): Clinic of Reproductive Endocrinology, University Hospital Zürich, Zürich, Switzerland

Montgomery, Scott, 1961- (author): Örebro universitet,Institutionen för medicinska vetenskaper,Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Clinical Epidemiology and Biostatistics, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

Nappi, Rossella E. (author): Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy; Research Center of Reproductive Medicine, IRCCS San Matteo Foundation, Pavia, Italy

Stenager, Egon (author): Department of Regional Research, University of Southern Denmark, Odense, Denmark; MS-Clinic of Southern Jutland (Aabenraa, Esbjerg, Kolding), Sønderborg, Denmark

Thompson, Heidi (author): Southern Health & Social Care Trust, Portadown, Northern Ireland

Tulek, Zeliha (author): Istanbul University-Cerrahpasa, Florence Nightingale Faculty of Nursing, Istanbul University-Cerrahpasa, Istanbul, Turkey

Verdun Di Cantogno, Elisabetta (author): EMD Serono Research & Development Institute, Inc., Billerica, MA, USA

Simoni, Manuela (author): Unit of Endocrinology, Department of Medical Specialties, University Hospital and Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy

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2024
2024
English.
In: Multiple Sclerosis Journal. - : Sage Publications. - 1352-4585 .- 1477-0970.

Related links:: https://doi.org/10.1...; show more...; https://urn.kb.se/re...; https://doi.org/10.1...; http://kipublication...; show less...

Research review (peer-reviewed)

Abstract Subject headings

BACKGROUND: Current guidance on the selection of appropriate contraception for people with multiple sclerosis (PwMS) is lacking.OBJECTIVE: To address this gap, an expert-led consensus program developed recommendations to support clinicians in discussing family planning and contraception with women and men with multiple sclerosis (MS).METHODS: A multidisciplinary steering committee (SC) of 13 international clinical experts led the program, supported by an extended faculty of 32 experts representing 18 countries. A modified Delphi methodology was used for decision-making and consensus-building. The SC drafted 15 clinical questions focused on patient-centered care, selection of contraception, and timing of stopping/starting contraception and disease-modifying therapies (DMTs). Statements addressing each question were drafted based on evaluation of published evidence and the experts' clinical experience. Consensus was reached if ⩾75% of respondents agreed (scoring 7-9 on a 9-point scale) with each recommendation.RESULTS: Consensus was reached on 24 of 25 proposed recommendations, including how and when to discuss contraception, types and safety of contraceptives, and how to evaluate the most appropriate contraceptive options for specific patient groups, including those with significant disability or being treated with DMTs.CONCLUSION: These expert recommendations provide the first practical, relevant, and comprehensive guidance for clinicians on the selection of contraception in PwMS.

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By the author/editor: Hillert, Jan; Bove, Riley; Haddad, Lisa B.; Hellwig, Kerstin; Houtchens, Maria; Magyari, Melinda; show more...; Merki-Feld, Gabr ...; Montgomery, Scot ...; Nappi, Rossella ...; Stenager, Egon; Thompson, Heidi; Tulek, Zeliha; Verdun Di Cantog ...; Simoni, Manuela; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Neurology

Articles in the publication: Multiple Scleros ...

By the university: Örebro University; Karolinska Institutet

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Expert opinion on the use of contraception in people with multiple sclerosis

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