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Randomized controll...
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Ferreira, CláudiaCINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal
(author)
Randomized controlled trial of an Acceptance and Commitment Therapy and compassion-based group intervention for persons with inflammatory bowel disease : the LIFEwithIBD intervention
- Article/chapterEnglish2024
Publisher, publication year, extent ...
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Frontiers Media S.A.2024
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LIBRIS-ID:oai:DiVA.org:oru-113745
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-113745URI
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https://doi.org/10.3389/fpsyg.2024.1367913DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Objectives: This study tested the acceptability and efficacy of an Acceptance and Commitment Therapy and compassion-based intervention (LIFEwithIBD) in people with IBD through a two-arm RCT.Methods: Participants were recruited at the Gastroenterology Department of the Coimbra University Hospital between June and September 2019. Of the 355 patients screened, those who accepted to participate were randomly assigned to one of two conditions: experimental group (LIFEwithIBD; n = 25) or control group (waitlist; n = 29). Participants completed self-report measures at baseline (T0), post-intervention (T1), and 3-month (T2) and 12-month (T3) follow-ups. Intervention acceptability was assessed. Efficacy was examined using intent-to-treat ANCOVA at post-intervention after adjusting for baseline values of depressive, anxiety, and stress symptoms (primary outcomes). Linear mixed models for all longitudinal outcomes were also analysed. Inflammatory and disease biomarkers were determined at T0 and T3.Results: Acceptability results revealed a high level of satisfaction and perceived usefulness regarding the intervention. Both groups experienced a significant decrease in stress symptoms and IBD symptom perception at T1. No significant differences were observed at follow-up for the primary outcomes. The experimental group reported significantly lower Crohn’s disease Symptom severity at T2 than the control group. Post-hoc analyses designed to mitigate floor effects revealed substantial treatment effects for the experimental group regarding anxiety symptoms. No significant differences were observed in clinical biomarkers from T0 to T3.Conclusion: The LIFEwithIBD intervention shows promising, although preliminary, benefits for managing disease activity and reducing anxiety symptoms in IBD patients with high severity of psychological distress.
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Pereira, JoanaCINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal
(author)
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Skvarc, DavidEMBRACE Lab, School of Behavioural, Social and Legal Sciences, University of Örebro, Örebro, Sweden
(author)
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Oliveira, SaraCINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal
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Galhardo, AnaCINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal; Instituto Superior Miguel Torga, Coimbra, Portugal
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Ferreira, Nuno B.School of Social Sciences, University of Nicosia, Nicosia, Cyprus
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Lucena-Santos, PaolaCINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal
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Carvalho, Sérgio A.CINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal; HEI-Lab: Digital Human-Environment Interaction Lab, School of Psychology and Life Sciences, Lusófona University, Lisbon, Portugal
(author)
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Matos-Pina, InêsCINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal
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Rocha, Bárbara S.Center for Neuroscience and Cell Biology, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal
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Portela, FranciscoCoimbra University Hospital [CHUC], Gastroenterology Service, Coimbra, Portugal
(author)
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Trindade, Ines,PhD,1990-Örebro universitet,Institutionen för beteende-, social- och rättsvetenskap,CINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal,EMBRACE Lab(Swepub:oru)ite
(author)
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CINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, PortugalEMBRACE Lab, School of Behavioural, Social and Legal Sciences, University of Örebro, Örebro, Sweden
(creator_code:org_t)
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In:Frontiers in Psychology: Frontiers Media S.A.151664-1078
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