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Sampling for Chlamydia trachomatis infection : a comparison of vaginal, first-catch urine, combined vaginal and first-catch urine and endocervical sampling
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- Falk, Lars, 1954- (author)
- Linköpings universitet,Östergötlands Läns Landsting,Hudkliniken i Östergötland,Forsknings- och utvecklingsenheten för Närsjukvården i Östergötland,Hälsouniversitetet
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- Coble, B-I (author)
- Östergötlands Läns Landsting,Hudkliniken i Östergötland
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- Mjornberg, P-A (author)
- Ryhov Cty Hosp, Dept Dermatol & Venereol, Jönköping, Sweden,Ryhov County Hospital, Jönköping
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- (creator_code:org_t)
- 2010-04-01
- 2010
- English.
- In: International Journal of STD and AIDS (London). - : SAGE Publications. - 0956-4624 .- 1758-1052. ; 21:4, s. 283-287
- Journal article (peer-reviewed)
Abstract
Subject headings
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- The aim of the study was to evaluate the sensitivity of patients' self-sampled vaginal specimens, first-catch urine (FCU), combined vaginal/FCU specimens and endocervical specimens for detecting chlamydial infection in women. Women attending sexually transmitted disease clinics, youth clinics and a women's health clinic were enrolled. They self-collected a vaginal specimen with two swabs, which were placed into a sterile tube and into a tube containing a buffer medium, respectively. An FCU sample was collected and aliquoted into both an empty tube and the tube containing the vaginal swab. A clinician collected an endocervical swab. The samples were sent to laboratories for analysis using polymerase chain reaction testing and strand displacement amplification testing, respectively. The sensitivities calculated in all 171 Chlamydia trachomatis-infected women were equal for endocervical specimens (97.1%), vaginal specimens (96.5%) and combined vaginal/FCU specimens (95.3%), whereas the sensitivity for FCU was significantly lower (87.7%). The sensitivity of vaginal specimens for the detection of C. trachomatis is as high as that of combined vaginal/FCU specimens.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Keyword
- sexually transmitted infections
- vaginal sampling
- chlamydia
- women
- MEDICINE
- MEDICIN
- Medicine
- Medicin
- Dermatology and venerology
Publication and Content Type
- ref (subject category)
- art (subject category)
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