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A time trend study ...
A time trend study of significantly elevated perfluorocarboxylate levels in humans after using fluorinated ski wax
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- Nilsson, Helena, 1974- (author)
- Örebro universitet,Akademin för naturvetenskap och teknik
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- Kärrman, Anna, 1975- (author)
- Örebro universitet,Akademin för naturvetenskap och teknik
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- Westberg, Håkan, 1949- (author)
- Örebro universitet,Akademin för naturvetenskap och teknik,Department of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden
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- Rotander, Anna, 1978- (author)
- Örebro universitet,Akademin för naturvetenskap och teknik
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- van Bavel, Bert, 1963- (author)
- Örebro universitet,Akademin för naturvetenskap och teknik
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- Lindström, Gunilla, 1949- (author)
- Örebro universitet,Akademin för naturvetenskap och teknik
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(creator_code:org_t)
- 2010-02-16
- 2010
- English.
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In: Environmental Science and Technology. - Washington, USA : American Chemical Society (ACS). - 0013-936X .- 1520-5851. ; 44:6, s. 2150-2155
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- A time trend study focusing on ski waxing technicians' exposure to perfluorinated chemicals (PFCs) from fluorinated wax fumes was performed in 2007/2008. Levels of eight perfluorocarboxylates and three perfluorosulfonates were analyzed in monthly blood samples from eight technicians, Samples were collected before the ski season, i.e., preseason, then at four AS World Cup competitions in cross country skiing, and finally during an unexposed 5-month postseason period. The perfluorinated carboxylates perfluoroheptanoic acid (PFHpA), perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), and perfluoroundecanoic acid (PFUnDA) bioaccumulate, and continued exposure may contribute to elevated levels in ski technicians compared to the general population. The wax technicians' median blood level of PFOA is 112 ng/mL compared to 2.5 ng/mL in the general Swedish population. A significant correlation was found between number of working years and levels of perfluorocarboxylates. The PFOA levels in three technicians with "low" initial levels of PFOA (< 10.0 ng/mL in preseason blood) increased by 254, 134, and 120%, whereas five technicians with "high" initial levels (> 100 ng/mL in preseason sample) were at steady state. PFHxA is suggested to have a short half-life in humans relative the other perfluorocarboxylates. The levels of perfluorosulfonates were unaffected by the wax exposure.
Subject headings
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
Keyword
- Chemistry
- Kemi
- Environmental chemistry
- Miljökemi
- Miljökemi
- Environmental Chemistry
- Chemistry
- Kemi
Publication and Content Type
- ref (subject category)
- art (subject category)
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Nilsson, Helena, ...
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Kärrman, Anna, 1 ...
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Westberg, Håkan, ...
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Rotander, Anna, ...
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van Bavel, Bert, ...
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Lindström, Gunil ...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Earth and Relate ...
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and Environmental Sc ...
- Articles in the publication
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Environmental Sc ...
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Örebro University