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Strategies to manag...
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Wedemeyer, H.Dept Gastroenterol Hepatol & Endocrinol, Hannover Med Sch, Hannover, Germany; German Liver Fdn, Hannover, Germany
(author)
Strategies to manage hepatitis C virus (HCV) disease burden
- Article/chapterEnglish2014
Publisher, publication year, extent ...
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2014-04-08
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Hoboken :Wiley-Blackwell,2014
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:oru-34996
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-34996URI
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https://doi.org/10.1111/jvh.12249DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:128663844URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding Agency:Gilead Sciences
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The number of hepatitis C virus (HCV) infections is projected to decline while those with advanced liver disease will increase. A modeling approach was used to forecast two treatment scenarios: (i) the impact of increased treatment efficacy while keeping the number of treated patients constant and (ii) increasing efficacy and treatment rate. This analysis suggests that successful diagnosis and treatment of a small proportion of patients can contribute significantly to the reduction of disease burden in the countries studied. The largest reduction in HCV-related morbidity and mortality occurs when increased treatment is combined with higher efficacy therapies, generally in combination with increased diagnosis. With a treatment rate of approximately 10%, this analysis suggests it is possible to achieve elimination of HCV (defined as a >90% decline in total infections by 2030). However, for most countries presented, this will require a 3-5 fold increase in diagnosis and/or treatment. Thus, building the public health and clinical provider capacity for improved diagnosis and treatment will be critical.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Duberg, Ann-Sofi,1957-Örebro universitet,Institutionen för läkarutbildning,Region Örebro län,Dept Infect Dis, Örebro University Hospital, Örebro, Sweden(Swepub:oru)adg
(author)
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Buti, M.CIBERehd, Hosp Valle De Hebron, Barcelona, Spain
(author)
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Rosenberg, W. M.Div Med, UCL Inst Liver & Digest Hlth, University College, London, London, England
(author)
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Frankova, S.Dept Hepatogastroenterol, Inst Clin & Expt Med, Prague, Czech Republic
(author)
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Esmat, G.Cairo Univ, Cairo, Egypt
(author)
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Ormeci, N.Ankara Univ, Ankara, Turkey
(author)
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Van Vlierberghe, H.Ghent Univ Hosp, Ghent, Belgium
(author)
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Gschwantler, M.Dept Internal Med 4, Wilhelminenspital Stadt Wien, Vienna, Austria
(author)
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Akarca, U.Ege Univ, Izmir, Turkey
(author)
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Aleman, S.Karolinska Institutet
(author)
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Balik, I.Ankara Univ, Ankara, Turkey
(author)
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Berg, T.Univ Leipzig, Leipzig, Germany
(author)
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Bihl, F.Dept Gastroenterol, Osped Cantonale, Bellinzona, Switzerland
(author)
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Bilodeau, M.Dept Med, Liver Unit, Univ Montreal, Montreal, Canada
(author)
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Blasco, A. J.Adv Tech Hlth Serv Res TAISS, Madrid, Spain
(author)
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Brandao Mello, C. E.Dept Gastroenterol, Fed Univ State Rio de Janeiro, Rio De Janeiro, Brazil
(author)
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Bruggmann, P.Arud Ctr Addict Med, Zurich, Switzerland
(author)
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Calinas, F.Ctr Hosp Lisboa Cent, Dept Gastroenterol, Hosp Santo Antonio Capuchos, Lisbon, Portugal
(author)
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Calleja, J. L.Hosp Puerta Hierro, Madrid, Spain
(author)
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Cheinquer, H.Hosp Clin, Univ Fed Rio Grande do Sul, Porto Alegre RS, Brazil
(author)
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Christensen, P. B.Dept Infect Dis, Odense Univ Hosp, Odense, Denmark
(author)
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Clausen, M.Region Hosp Hovedstaden, Region Hovedstaden, Hillerød, Denmark
(author)
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Coelho, H. S. M.Dept Clin Med, Univ Fed Rio de Janeiro, Rio De Janeiro, Brazil
(author)
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Cornberg, M.Dept Gastroenterol Hepatol & Endocrinol, Hannover Med Sch, Hannover, Germany; German Liver Fdn, Hannover, Germany
(author)
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Cramp, M. E.Peninsula Sch Med & Dent, Univ Plymouth, Plymouth, England
(author)
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Dore, G. J.Kirby Inst, Univ New S Wales, Sydney NSW, Australia
(author)
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Doss, W.Cairo Univ, Cairo, Egypt
(author)
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El-Sayed, M. H.Ain Shams Univ, Cairo, Egypt
(author)
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Ergor, G.Dokuz Eylul Univ, Izmir, Turkey
(author)
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Estes, C.Ctr Dis Anal CDA, Louisville CO, USA
(author)
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Falconer, K.Karolinska Institutet
(author)
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Felix, J.Exigo Consultores, Alhos Vedros, Portugal
(author)
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Ferraz, M. L. G.Div Gastroenterol, Univ Fed Sao Paulo, Sao Paulo, Brazil
(author)
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Ferreira, P. R.Div Infect Dis, Univ Fed Sao Paulo, Sao Paulo, Brazil
(author)
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Garcia-Samaniego, J.Biomedical Research Networking Center in Hepatic and Digestive Diseases, Hosp Carlos III, Madrid, Spain
(author)
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Gerstoft, J.Univ Copenhagen, Copenhagen, Denmark
(author)
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Giria, J. A.Direccao Geral Saude, Lisbon, Portugal
(author)
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Goncales, F. L., Jr.Fac Ciencias Med, Disciplina Doencas Infecciosas, Grp Estudo Hepatites,Dept Clin Med, Univ Estadual Campinas, Sao Paulo, Brazil
(author)
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Guimaraes Pessoa, M.Sch Med, Div Gastroenterol & Hepatol, Univ Sao Paulo, Sao Paulo, Brazil
(author)
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Hezode, C.Serv Hepatogastroenterol, Hop Henri Mondor, Creteil, France
(author)
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Hindman, S. J.Dept Med Huddinge, Karolinska Inst, Stockholm, Sweden; Infect Dis Unit, Karolinska Univ Hosp, Stockholm, Sweden
(author)
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Hofer, H.Div Gastroenterol & Hepatol, Dept Internal Med 3, Med Univ Vienna, Vienna, Austria
(author)
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Husa, P.Clin Infect Dis, Univ Hosp Brno, Masaryk Univ, Brno, Czech Republic
(author)
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Idilman, R.Dept Gastroenterol, Sch Med, Ankara Univ, Ankara, Turkey
(author)
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Kåberg, M.Karolinska Institutet
(author)
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Kaita, K. D. E.Dept Internal Med, Sect Hepatol, Univ Manitoba, Winnipeg MB, Canada; Viral Hepatitis Invest Unit, Hlth Sci Ctr, Winnipeg MB, Canada
(author)
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Kautz, A.European Liver Patients Assoc, St Truiden, Belgium
(author)
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Kaymakoglu, S.Istanbul Univ, Istanbul, Turkey
(author)
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Krajden, M.British Columbia Ctr Dis Control, Univ British Columbia, Vancouver, Canada
(author)
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Krarup, H.Dept Med Gastroenterol, Aalborg Univ Hosp, Aalborg, Denmark; Sect Mol Diagnost, Aalborg Univ Hosp, Aalborg, Denmark
(author)
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Laleman, W.Univ Hosp Leuven, Katholieke Univ Leuven, Louvain, Belgium
(author)
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Lavanchy, D.
(author)
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Lazaro, P.Adv Tech Hlth Serv Res TAISS, Madrid, Spain
(author)
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Marinho, R. T.Ctr Hosp Lisboa Cent, Dept Gastroenterol, Hosp Santo Antonio Capuchos, Lisbon, Portugal
(author)
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Marotta, P.Div Gastroenterol, Univ Western Ontario, London ON, Canada
(author)
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Mauss, S.Univ Dusseldorf, Dusseldorf, Germany
(author)
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Mendes Correa, M. C.Sch Med, Univ Sao Paulo, Sao Paulo, Brazil
(author)
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Moreno, C.Erasme Univ Hosp, Univ Libre Brussels, Brussels, Belgium
(author)
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Muellhaupt, B.Swiss HPB Hepatopancreatobiliary Ctr, Univ Zurich Hosp, Zurich, Switzerland; Dept Gastroenterol & Hepatol, Univ Zurich Hosp, Zurich, Switzerland
(author)
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Myers, R. P.Div Gastroenterol & Hepatol, Liver Unit, Univ Calgary, Calgary AB, Canada
(author)
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Nemecek, V.Natl Reference Lab Hepatitis, Natl Inst Publ Hlth, Prague, Czech Republic
(author)
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Ovrehus, A. L. H.Dept Infect Dis, Odense Univ Hosp, Odense, Denmark
(author)
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Parkes, J.Univ Southhampton, Southampton, England
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Peltekian, K. M.Queen Elizabeth II Hlth Sci Ctr, Capital Dist Hlth Author, Dept Med, Dalhousie Univ & Hepatol Serv, Halifax NS, Canada; Queen Elizabeth II Hlth Sci Ctr, Capital Dist Hlth Author, Dept Surg, Dalhousie Univ & Hepatol Serv, Halifax NS, Canada
(author)
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Ramji, A.Dept Gastroenterol, Univ British Columbia, Vancouver, Canada
(author)
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Razavi, H.Ctr Dis Anal CDA, Louisville CO, USA
(author)
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Reis, N.Assembleia Republ, Lisbon, Portugal
(author)
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Roberts, S. K.Alfred Hosp, Melbourne Vic, Australia; Monash Univ, Melbourne, Australia
(author)
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Roudot-Thoraval, F.Dept Sante Publ, Hop Henri Mondor, Creteil, France
(author)
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Ryder, S. D.Nottingham Univ Hosp NHS Trust, Nottingham, England; Biomed Res Unit, Nottingham, England
(author)
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Sarmento-Castro, R.Dept Infect Dis, Ctr Hosp Porto, Oporto, Portugal
(author)
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Sarrazin, C.JW Goethe Univ Hosp, Frankfurt, Germany
(author)
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Semela, D.Div Gastroenterol & Hepatol, Cantonal Hosp St Gallen, St Gallen, Switzerland
(author)
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Sherman, M.Univ Hlth Network, Univ Toronto, Toronto Gen Hosp, Toronto, Canada
(author)
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Shiha, G. E.Egyptian Liver Res Inst & Hosp ELRIAH, Dakahliah, Egypt
(author)
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Sperl, J.Dept Hepatogastroenterol, Inst Clin & Expt Med, Prague, Czech Republic
(author)
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Starkel, P.Clin Univ St Luc, Catholic Univ Louvain, Brussels, Belgium
(author)
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Stauber, R. E.Med Univ Graz, Div Gastroenterol & Hepatol, Dept Internal Med, Graz, Austria
(author)
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Thompson, A. J.St Vincents Hosp, Dept Gastroenterol, Melbourne Vic, Australia; Univ Melbourne, Melbourne Vic, Australia
(author)
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Urbanek, P.Dept Internal Med, Fac Med 1, Charles Univ, Prague, Czech Republic; Cent Mil Hosp, Prague, Czech Republic
(author)
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Van Damme, P.Univ Antwerp, Antwerp, Belgium
(author)
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van Thiel, I.European Liver Patients Assoc, St Truiden, Belgium; Deutsch Leberhilfe eV, Cologne, Germany
(author)
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Vandijck, D.Univ Ghent, Dept Hlth Econ & Patient Safety, Ghent, Belgium; Hasselt Univ, Diepenbeek, Belgium
(author)
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Vogel, W.Med Univ Innsbruck, Innsbruck, Austria
(author)
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Waked, I.Natl Liver Inst, Menoufia, Egypt
(author)
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Weis, N.Copenhagen Univ Hosp, Hvidovre, Denmark
(author)
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Wiegand, J.Univ Leipzig, Leipzig, Germany
(author)
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Yosry, A.Cairo Univ, Cairo, Egypt
(author)
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Zekry, A.Univ New S Wales, St George Hosp Clin Sch Med, Sydney, NSW, Australia; Univ New S Wales, Sch Med Sci, Sydney, NSW, Australia
(author)
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Negro, F.Univ Hosp, Div Gastroenterol & Hepatol, Geneva, Switzerland; Monash Hlth, Melbourne Vic, Australia
(author)
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Sievert, W.Monash Hlth, Melbourne Vic, Australia; Monash Univ, Melbourne, Australia
(author)
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Gower, E.Ctr Dis Anal CDA, Louisville CO, USA
(author)
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Dept Gastroenterol Hepatol & Endocrinol, Hannover Med Sch, Hannover, Germany; German Liver Fdn, Hannover, GermanyInstitutionen för läkarutbildning
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In:Journal of Viral HepatitisHoboken : Wiley-Blackwell21, s. 60-891352-05041365-2893
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Wedemeyer, H.
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Rosenberg, W. M.
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Frankova, S.
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Krajden, M.
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Parkes, J.
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Razavi, H.
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Sarrazin, C.
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Sperl, J.
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Stauber, R. E.
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Thompson, A. J.
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Urbanek, P.
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Van Damme, P.
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van Thiel, I.
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Vandijck, D.
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Vogel, W.
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Waked, I.
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Weis, N.
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Wiegand, J.
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Yosry, A.
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Karolinska Institutet