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Nine-gene molecular...
Nine-gene molecular signature is not associated with prostate cancer death in a watchful waiting cohort
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Mucci, Lorelei A. (author)
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- Pawitan, Yudi (author)
- Karolinska Institutet
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Demichelis, Francesca (author)
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- Fall, Katja (author)
- Karolinska Institutet
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Stark, Jennifer R. (author)
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- Adami, Hans-Olov (author)
- Karolinska Institutet
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- Andersson, Swen-Olof (author)
- Örebro universitet,Hälsoakademin
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- Andrén, Ove (author)
- Örebro universitet,Hälsoakademin
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Eisenstein, Anna S. (author)
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- Holmberg, Lars (author)
- Uppsala universitet,Endokrinkirurgi
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Huang, Wei (author)
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Kantoff, Philip W. (author)
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Perner, Sven (author)
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Stampfer, Meir J. (author)
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- Johansson, Jan-Erik (author)
- Örebro universitet,Hälsoakademin
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Rubin, Mark A. (author)
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(creator_code:org_t)
- Baltimore : Waverly Press, 2008
- 2008
- English.
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In: Cancer Epidemiology, Biomarkers and Prevention. - Baltimore : Waverly Press. - 1055-9965 .- 1538-7755. ; 17:1, s. 249-251
- Related links:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Tumor molecular markers hold promise to distinguish potentially lethal from indolent prostate cancer and to guide treatment choices. A previous study identified a nine-gene molecular signature in tumors associated with prostate-specific antigen relapse after prostatectomy. We examined this molecular model in relation to prostate cancer death among 172 men with initially localized disease. We quantified protein expression of the nine genes in tumors to classify progression risk. Accounting for clinical prognostic factors, the nine-gene model did not provide discrimination to predict lethal and indolent prostate cancer.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Keyword
- Aged
- Cohort Studies
- Gene Expression Profiling/*methods
- Humans
- Immunoenzyme Techniques
- Male
- Prostate-Specific Antigen/blood
- Prostatic Neoplasms/epidemiology/*metabolism/*mortality
- Survival Rate
- Tissue Array Analysis
- Tumor Markers; Biological/*metabolism
- MEDICINE
- MEDICIN
- Oncology
- Onkologi
- Urology and andrology
- Urologi och andrologi
- Onkologi
- Oncology
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Mucci, Lorelei A ...
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Pawitan, Yudi
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Demichelis, Fran ...
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Fall, Katja
-
Stark, Jennifer ...
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Adami, Hans-Olov
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show more...
-
Andersson, Swen- ...
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Andrén, Ove
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Eisenstein, Anna ...
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Holmberg, Lars
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Huang, Wei
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Kantoff, Philip ...
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Perner, Sven
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Stampfer, Meir J ...
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Johansson, Jan-E ...
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Rubin, Mark A.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Urology and Neph ...
- Articles in the publication
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Cancer Epidemiol ...
- By the university
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Örebro University
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Uppsala University
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Karolinska Institutet