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- Coorevits, PascalGhent University, Ghent, Belgium; The European Institute for Health Records (EuroRec), Sint-Martens-Latem, Belgium (author)
Electronic health records : new opportunities for clinical research
- Article/chapterEnglish2013
Publisher, publication year, extent ...
- 2013-10-18
- Wiley-Blackwell,2013
- electronicrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:oru-41749
- https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-41749URI
- https://doi.org/10.1111/joim.12119DOI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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Notes
- Clinical research is on the threshold of a new era in which electronic health records (EHRs) are gaining an important novel supporting role. Whilst EHRs used for routine clinical care have some limitations at present, as discussed in this review, new improved systems and emerging research infrastructures are being developed to ensure that EHRs can be used for secondary purposes such as clinical research, including the design and execution of clinical trials for new medicines. EHR systems should be able to exchange information through the use of recently published international standards for their interoperability and clinically validated information structures (such as archetypes and international health terminologies), to ensure consistent and more complete recording and sharing of data for various patient groups. Such systems will counteract the obstacles of differing clinical languages and styles of documentation as well as the recognized incompleteness of routine records. Here, we discuss some of the legal and ethical concerns of clinical research data reuse and technical security measures that can enable such research while protecting privacy. In the emerging research landscape, cooperation infrastructures are being built where research projects can utilize the availability of patient data from federated EHR systems from many different sites, as well as in international multilingual settings. Amongst several initiatives described, the EHR4CR project offers a promising method for clinical research. One of the first achievements of this project was the development of a protocol feasibility prototype which is used for finding patients eligible for clinical trials from multiple sources.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Annan hälsovetenskap hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences Other Health Sciences hsv//eng
- Informatics
- Informatik
Added entries (persons, corporate bodies, meetings, titles ...)
- Sundgren, MAstraZeneca R&D, Mölndal, Sweden (author)
- Klein, Gunnar O.,1953-University of Science and Technology, Trondheim, Norway,eHälsa(Swepub:oru)grkn (author)
- Bahr, ASanofi R&D, Chilly-Mazarin, France (author)
- Claerhout, BCustodix NV, Sint-Martens-Latem, Belgium (author)
- Daniel, CParis Descartes University INSERM, Paris, France (author)
- Dugas, MUniversity of Münster, Münster, Germany (author)
- Dupont, DData Mining International SA, Geneva, Switzerland (author)
- Schmidt, APharma Product Development, F Hoffmann-La Roche Ltd, Basel, Switzerland (author)
- Singleton, PCambridge Health Informatics, Cambridge, UK (author)
- De Moor, GGhent University, Ghent, Belgium; The European Institute for Health Records (EuroRec), Sint-Martens-Latem, Belgium (author)
- Kalra, DUniversity College London, London, UK (author)
- Ghent University, Ghent, Belgium; The European Institute for Health Records (EuroRec), Sint-Martens-Latem, BelgiumAstraZeneca R&D, Mölndal, Sweden (creator_code:org_t)
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- In:Journal of Internal Medicine: Wiley-Blackwell274:6, s. 547-600954-68201365-2796
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