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High cardiovascular fitness is associated with low metabolic risk score in children : the European Youth Heart Study

Ruiz, Jonatan R. (author)
Karolinska Institutet
Ortega, Francisco B. (author)
Karolinska Institutet
Rizzo, Nico S. (author)
Karolinska Institutet
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Villa, Inga (author)
Hurtig-Wennlöf, Anita (author)
Örebro universitet,Institutionen för klinisk medicin
Oja, Leila (author)
Sjöström, Michael (author)
Karolinska Institutet
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 (creator_code:org_t)
Baltimore, Md : Williams and Wilkins Co, 2007
2007
English.
In: Pediatric Research. - Baltimore, Md : Williams and Wilkins Co. - 0031-3998 .- 1530-0447. ; 61:3, s. 350-355
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The aim of the present study was to examine the associations of cardiovascular fitness (CVF) with a clustering of metabolic risk factors in children, and to examine whether there is a CVF level associated with a low metabolic risk. CVF was estimated by a maximal ergometer bike test on 873 randomly selected children from Sweden and Estonia. Additional measured outcomes included fasting insulin, glucose, triglycerides, HDLC, blood pressure, and the sum of five skinfolds. A metabolic risk score was computed as the mean of the standardized outcomes scores. A risk score <75th percentile was considered to indicate a low metabolic risk. CVF was negatively associated with clustering of metabolic risk factors in children. Receiver operating characteristic curve analysis showed a significant discriminatory accuracy of CVF in identifying the low/high metabolic risk in girls and boys (p < 0.001). The CVF level for a low metabolic risk was 37.0 and 42.1 mL/kg/min in girls and boys, respectively. These levels are similar to the health-related threshold values of CVF suggested by worldwide recognized organizations. In conclusion, the results suggest a hypothetical CVF level for having a low metabolic risk, which should be further tested in longitudinal and/or intervention studies. Abbreviations: AUC, area under the curve CVF, cardiovascular fitness ROC, receiver operating characteristic

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Keyword

Cardiovascular Diseases/etiology/physiopathology
Cardiovascular Physiology
Child
Cross-Sectional Studies
Europe
Exercise Test
Female
Humans
Male
Metabolic Syndrome X/etiology/physiopathology
Physical Fitness/*physiology
Risk Factors
MEDICINE
MEDICIN
Internal medicine
Invärtesmedicin
Paediatric medicine
Pediatrisk medicin
Cardiovascular medicine
Kardiovaskulär medicin
Pediatrik
Pediatrics

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ref (subject category)
art (subject category)

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